Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16153732 | 0.81 | CYP1A2 (0.45) | EGFRERBB2HSP90AA1CYP1A2CYP2C9 | |
| SCHEMBL30810286 | 0.79 | ALDH1A1 (0.55) | HSD17B10ACLYCYP3A4ALDH1A1TSHR | |
| SCHEMBL3214124 | 0.74 | HSD17B10 (0.50) | EGFRERBB2HSP90AA1CYP1A2CYP2C9 | |
| SCHEMBL13186081 | 0.73 | MEN1 (0.39) | EGFRERBB2ALDH1A1TSHRMEN1 | |
| SCHEMBL15702597 | 0.71 | EGFR (0.60) | EGFRERBB2HSP90AA1CYP1A2CYP2C9 | |
| SCHEMBL12305659 | 0.70 | CYP1A2 (0.53) | EGFRERBB2HSP90AA1CYP1A2CYP2C9 | |
| SCHEMBL13219272 | 0.69 | HSP90AA1 (0.44) | EGFRERBB2HSP90AA1CYP1A2CYP2C9 | |
| SCHEMBL13186086 | 0.69 | CYP2C19 (0.47) | HSP90AA1CYP1A2CYP2C9HSD17B10CYP2D6 | |
| SCHEMBL9993152 | 0.68 | HSD17B10 (0.56) | EGFRERBB2HSP90AA1CYP1A2CYP2C9 | |
| SCHEMBL13888086 | 0.68 | HSD17B10 (0.56) | EGFRERBB2HSP90AA1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140303333-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | UNIV PRINCE EDWARD ISLAND (CA) | 2014-10-09 | — | — | US | disclosed |
| US-20140303333-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | UNIV PRINCE EDWARD ISLAND (CA) | 2014-10-09 | — | — | US | disclosed |
| WO-2013053046-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | UNIVERSITY OF PRINCE EDWARD ISLAND (CA) | 2013-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303333-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | TFRC, PCBP1, FECH | EGFR 2482/4885ERBB2 1959/4885HSP90AA1 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.