Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738560 | 0.77 | PARP1 (0.39) | TP53HPGDKMT2ATLR9 | |
| SCHEMBL5870552 | 0.73 | HPGD (0.39) | TP53HPGDKMT2AMGLL | |
| SCHEMBL2552173 | 0.68 | MGLL (0.53) | MGLLTLR9 | |
| SCHEMBL13056396 | 0.64 | TLR9 (0.74) | TP53HPGDKMT2AMGLLTLR9 | |
| SCHEMBL11240815 | 0.64 | TLR9 (0.39) | MGLLTLR9 | |
| SCHEMBL9596870 | 0.64 | TLR9 (0.44) | MGLLTLR9 | |
| SCHEMBL28755352 | 0.63 | TLR9 (0.45) | KMT2AMGLLTLR9 | |
| SCHEMBL19511775 | 0.63 | TLR9 (0.47) | HPGDKMT2AMGLLTLR9 | |
| Methane SCHEMBL28470438 | 0.61 | MGLL (0.50) | MGLLTLR9 | |
| SCHEMBL11144342 | 0.58 | MGLL (0.49) | HPGDMGLLTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024062090-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |
| EP-3849956-A1 | FLUORINATION METHOD | Oxford University Innovation Limited (GB) | 2021-07-21 | — | — | EP | disclosed |
| EP-3824285-A1 | MOLECULAR HOPPER | Oxford University Innovation Limited (GB) | 2021-05-26 | — | — | EP | disclosed |
| EP-3801630-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | MEDIMMUNE LIMITED (GB) | 2021-04-14 | — | — | EP | disclosed |
| EP-3774699-A1 | RADIOLABELLED COMPOUND | Oxford University Innovation Limited (GB) | 2021-02-17 | — | — | EP | disclosed |
| EP-3774820-A1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF AS ANTITUMOUR AGENTS | MedImmune Limited (GB) | 2021-02-17 | — | — | EP | disclosed |
| WO-2020245283-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | ADC THERAPEUTICS SA (CH) | 2020-12-10 | — | — | WO | disclosed |
| EP-3710066-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | Medimmune Limited (GB) | 2020-09-23 | — | — | EP | disclosed |
| EP-3668874-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | Medimmune Limited (GB) | 2020-06-24 | — | — | EP | disclosed |
| WO-2020079239-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | MEDIMMUNE LIMITED (GB) | 2020-04-23 | — | — | WO | disclosed |
| WO-2003059885-A1 | THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-07-24 | — | — | WO | disclosed |
| EP-1328510-A2 | CARBAMIC ACID COMPOUNDS COMPRISING A SULFONAMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LTD. (GB) | 2003-07-23 | — | — | EP | disclosed |
| WO-2003029176-A1 | 4-(C2-6ALKOXY)-SUBSTITUTED CHALCONES AS THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-04-10 | — | — | WO | disclosed |
| WO-2003024949-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| WO-2003015790-A1 | THIOPYRANE-4-ONES AS DNA PROTEIN KINASE INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-02-27 | — | — | WO | disclosed |
| WO-2002030879-A2 | CARBAMIC ACID COMPOUNDS COMPRISING A SULFONAMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030932-A2 | N8,N13-DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002026696-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002026703-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN ETHER LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002008193-A2 | THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-01-31 | — | — | WO | disclosed |