Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901236 | 0.94 | TLR9 (0.49) | TLR9ALDH1A1PKMHSP90AA1CCR6 | |
| SCHEMBL28343039 | 0.89 | ALDH1A1 (0.56) | TLR9ALDH1A1PKMHSP90AA1CCR6 | |
| SCHEMBL9262225 | 0.79 | GAA (0.55) | TLR9ALDH1A1PKMHSP90AA1CCR6 | |
| SCHEMBL15636976 | 0.78 | ALDH1A1 (0.43) | ALDH1A1PKMTDP1CA12CA1 | |
| SCHEMBL11564833 | 0.78 | ALDH1A1 (0.43) | ALDH1A1PKMTDP1CA12CA1 | |
| SCHEMBL5576207 | 0.77 | PKM (0.40) | TLR9ALDH1A1PKMHSP90AA1CCR6 | |
| SCHEMBL317656 | 0.76 | TTR (0.44) | ALDH1A1PKMATMCA12CA1 | |
| SCHEMBL28019596 | 0.74 | MEN1 (0.37) | TLR9ALDH1A1PKMHSP90AA1CCR6 | |
| SCHEMBL9125621 | 0.74 | TLR9 (0.77) | TLR9ALDH1A1PKMHSP90AA1CCR6 | |
| SCHEMBL183052 | 0.73 | ALDH1A1 (0.71) | TLR9ALDH1A1PKMHSP90AA1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779465-B | Oligonucleotides for reducing PD-L1 expression | 豪夫迈·罗氏有限公司 | 2022-05-13 | — | — | CN | disclosed |