Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490422 | 1.00 | MEN1 (0.47) | MEN1KMT2AHCRTR1HCRTR2KCNH2 | |
| SCHEMBL13490307 | 0.90 | NPC1 (0.51) | MEN1KMT2AHCRTR1HCRTR2CXCR6 | |
| SCHEMBL3213604 | 0.90 | MEN1 (0.51) | MEN1KMT2AHCRTR1HCRTR2CXCR6 | |
| SCHEMBL13490421 | 0.88 | MEN1 (0.48) | MEN1KMT2AHCRTR1HCRTR2CXCR6 | |
| SCHEMBL13490319 | 0.88 | MEN1 (0.48) | MEN1KMT2AHCRTR1HCRTR2CXCR6 | |
| SCHEMBL3222191 | 0.88 | GRM5 (0.52) | MEN1KMT2AHCRTR1HCRTR2KCNH2 | |
| SCHEMBL3217312 | 0.88 | MEN1 (0.48) | MEN1KMT2AHCRTR1HCRTR2CXCR6 | |
| SCHEMBL13490309 | 0.87 | MEN1 (0.47) | MEN1KMT2ACXCR6GRM5MAPT | |
| SCHEMBL13490741 | 0.86 | MEN1 (0.54) | MEN1KMT2ACXCR6GRM5MAPT | |
| SCHEMBL13490372 | 0.86 | MEN1 (0.54) | MEN1KMT2ACXCR6GRM5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | MEN1 2892/4885KMT2A 1782/4885HCRTR1 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.