SCHEMBL3214593

SCHEMBL3214593

CCCCNCc1ccccc1C1C=Cc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.43
CHRM2 P08172 5/20 0.40
BCHE P06276 3/20 0.39
ACHE P22303 3/20 0.39
CA12 O43570 4/20 0.38
CA2 P00918 4/20 0.38
CA9 Q16790 4/20 0.38
KDM4E B2RXH2 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GRIN1 Q05586 3/20 0.37
GRIN2A Q12879 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29949318 0.82 CYSLTR2 (0.40) SIGMAR1CHRM2BCHEACHEKDM4E
SCHEMBL6055996 0.82 CYSLTR2 (0.40) SIGMAR1CHRM2BCHEACHEKDM4E
SCHEMBL27740455 0.78 SIGMAR1 (0.38) SIGMAR1CHRM2KDM4ETSHRHSD17B10
SCHEMBL3190427 0.77 SIGMAR1 (0.38) SIGMAR1CHRM2BCHEACHEKDM4E
SCHEMBL3213472 0.75 CHRM2 (0.41) CHRM2BCHEACHETSHRGRIN1
SCHEMBL3202576 0.75 BCHE (0.53) CHRM2BCHEACHECA12CA2
SCHEMBL3204622 0.75 SIGMAR1 (0.36) SIGMAR1CHRM2KDM4EHSD17B10
SCHEMBL4622458 0.75 BCHE (0.41) SIGMAR1CHRM2BCHEACHEKDM4E
SCHEMBL3213267 0.74 BCHE (0.36) SIGMAR1CHRM2BCHEACHEKDM4E
SCHEMBL8729002 0.74 SIGMAR1 (0.47) SIGMAR1CHRM2BCHEACHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 SIGMAR1 1272/4885CHRM2 517/4885BCHE 4295/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 SIGMAR1 1272/4885CHRM2 517/4885BCHE 4295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.