SCHEMBL3202576

SCHEMBL3202576

CCCCNCc1ccccc1C1c2ccccc2-c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.53
ACHE P22303 5/20 0.53
CHRM2 P08172 11/20 0.42
CA12 O43570 4/20 0.41
CA2 P00918 4/20 0.41
CA9 Q16790 4/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GRIN1 Q05586 4/20 0.40
GRIN2A Q12879 4/20 0.40
TP53 P04637 1/20 0.40
CHRM4 P08173 1/20 0.40
CYP3A4 P08684 1/20 0.40
CHRM5 P08912 1/20 0.40
CYP2D6 P10635 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
THPO P40225 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3213472 0.79 CHRM2 (0.41) BCHEACHECHRM2TSHRGRIN1
SCHEMBL3191592 0.76 BCHE (0.44) BCHEACHEHSD17B10CYP2D6
SCHEMBL3208324 0.76 SCN8A (0.38) BCHEACHECHRM2TSHRKDM4E
SCHEMBL23864028 0.75 CHRM2 (0.49) BCHEACHECHRM2CA12CA2
SCHEMBL21799866 0.75 CHRM2 (0.49) BCHEACHECHRM2CA12CA2
SCHEMBL3214593 0.75 SIGMAR1 (0.43) BCHEACHECHRM2CA12CA2
SCHEMBL10455243 0.74 HTR2A (0.45) BCHEACHECHRM2CA2CYP2D6
SCHEMBL5013296 0.73 CHRM2 (0.76) BCHEACHECHRM2CA12CA2
SCHEMBL9784389 0.73 CHRM2 (0.72) CHRM2CA12CA2CA9TSHR
SCHEMBL3845684 0.73 BCHE (0.50) BCHEACHECHRM2CA2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed