SCHEMBL3214871

SCHEMBL3214871

CC1=C(C)C(C)C(c2ccccc2C(=N)C2CCCCC2)=C1C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
CYP2C19 P33261 1/20 0.31
LTB4R2 Q9NPC1 1/20 0.31
P2RX7 Q99572 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201476 0.85 L3MBTL1 (0.32) NPC1RAB9AALDH1A1
SCHEMBL16229941 0.82 SPHK1 (0.36) HPGDTSHRNPC1RAB9ACYP2C19
SCHEMBL3208235 0.80 PSMB5 (0.32) NPC1RAB9ASMN1; SMN2
SCHEMBL3202746 0.80 NPC1 (0.33) NPC1RAB9ACYP2C19MEN1KMT2A
SCHEMBL3216950 0.79 TAS1R3 (0.38) HPGDRAB9ACYP2C19MEN1KMT2A
SCHEMBL17721318 0.78
SCHEMBL3199740 0.74 CYP1A2 (0.37)
SCHEMBL3193105 0.74
SCHEMBL3216507 0.74 NPC1 (0.32) HPGDTSHRNPC1RAB9ACYP2C19
SCHEMBL3204134 0.73 NPC1 (0.31) HPGDTSHRNPC1RAB9ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed