Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214779 | 0.88 | AAK1 (0.33) | AAK1HPGDSRAB9ASCN9ASMN1; SMN2 | |
| SCHEMBL3214599 | 0.88 | MALT1 (0.37) | AAK1HPGDSSCN9ACYP1A2CYP3A4 | |
| SCHEMBL3215001 | 0.86 | PDGFRB (0.33) | AAK1RAB9ALMNAMAP3K5PDGFRB | |
| SCHEMBL633389 | 0.83 | HPGDS (0.38) | AAK1HPGDSRAB9ASCN9ASMN1; SMN2 | |
| SCHEMBL13078307 | 0.78 | CYP1A2 (0.32) | AAK1HPGDSCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1926931 | 0.77 | KDM4E (0.32) | AAK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1927712 | 0.77 | CYP1A2 (0.33) | AAK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1927896 | 0.77 | ALOX5AP (0.31) | AAK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3214890 | 0.75 | HPGDS (0.33) | HPGDSSCN9APDGFRBPDGFRA | |
| SCHEMBL2879160 | 0.74 | HPGDS (0.32) | HPGDSSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056570-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2068632-A1 | FUNGICIDES | Syngeta Participations AG (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008028624-A1 | FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056570-A1 | FUNGICIDES | CYP21A2, CYP51A1, CYP4X1 | AAK1 4678/4885HPGDS 4806/4885RAB9A 2344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.