Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15709233 | 0.85 | KDM4E (0.36) | ALDH1A1ALDH1A3KDM4EAOX1RBP4 | |
| SCHEMBL326281 | 0.78 | MCHR1 (0.69) | KCNH2MCHR1 | |
| Formic Acid SCHEMBL320885 | 0.77 | MCHR1 (0.61) | KCNH2MCHR1OXTRAVPR1ARBP4 | |
| SCHEMBL3680153 | 0.77 | PDE4B (0.45) | ALDH1A1ALDH1A3TSHRHPGD | |
| SCHEMBL15709111 | 0.77 | RBP4 (0.35) | ALDH1A1KDM4EAOX1RBP4TSHR | |
| SCHEMBL23442879 | 0.76 | PDE4B (0.46) | ALDH1A1ALDH1A3KDM4EAOX1TSHR | |
| SCHEMBL16272283 | 0.76 | ALDH1A3 (0.45) | ALDH1A1ALDH1A3TSHRHPGD | |
| SCHEMBL10264486 | 0.75 | MCHR1 (0.58) | KCNH2MCHR1HRH3 | |
| SCHEMBL15709284 | 0.75 | BCL9 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL23301267 | 0.75 | SRC (0.44) | ALDH1A1TRIM24HPGDTRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590969-A2 | THERAPEUTIC AGENTS 976 | AstraZeneca AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004588-A2 | THERAPEUTIC AGENTS 976 | ASTRAZENECA AB (SE) | 2012-01-12 | — | — | WO | disclosed |