SCHEMBL321518

SCHEMBL321518

CCCCCCCCc1ccsc1-c1sc(-c2sccc2CCCCCCCC)c2sc(C(=O)C(CC)CCCC)cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.39
S1PR1 P21453 1/20 0.31
TSHR P16473 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX5 P09917 1/20 0.31
MAPT P10636 1/20 0.31
TYR P14679 1/20 0.31
ALOX15 P16050 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GAA P10253 1/20 0.31
XBP1 P17861 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYSLTR2 Q9NS75 3/20 0.30
CYSLTR1 Q9Y271 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320979 0.84 GPR35 (0.36) GPR35CYSLTR2CYSLTR1
SCHEMBL320991 0.84 PRSS1 (0.43) GPR35TSHRCYP3A4HTTTDP1
SCHEMBL10076363 0.77 TSHR (0.38) TSHRMEN1MAPTALOX15HTT
SCHEMBL15187518 0.77 GPR35 (0.32) GPR35
SCHEMBL10077128 0.77
SCHEMBL321048 0.73 GAA (0.33) MEN1TP53MAPTKMT2AGAA
SCHEMBL15187525 0.71
SCHEMBL722288 0.69 LIPG (0.44) GPR35TSHRMEN1TP53CYP3A4
SCHEMBL14267185 0.69 LIPG (0.44) GPR35TSHRMEN1TP53CYP3A4
SCHEMBL9242673 0.69 LIPG (0.44) GPR35TSHRMEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9287505-B2 Semiconducting polymers MERCK PATENT GMBH (DE) 2016-03-15 US disclosed
US-9287505-B2 Semiconducting polymers MERCK PATENT GMBH (DE) 2016-03-15 US disclosed
US-20130207045-A1 SEMICONDUCTING POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-08-15 US disclosed
US-20130207045-A1 SEMICONDUCTING POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-08-15 US disclosed
EP-2590986-A2 SEMICONDUCTING POLYMERS Merck Patent GmbH (DE) 2013-05-15 EP disclosed
WO-2012003919-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2012-01-12 WO disclosed
WO-2012003919-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2012-01-12 WO disclosed