Isopropylamine

Isopropylamine

SCHEMBL3215229

CC(C)N.CC(C)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Alcohol SCHEMBL635742 0.89
Isopropylamine SCHEMBL141428 0.82
Isopropyl Alcohol SCHEMBL2590415 0.82
Isopropyl Alcohol SCHEMBL10579294 0.82
Isopropylamine SCHEMBL3988067 0.82
SCHEMBL13208844 0.82
Isopropyl Alcohol SCHEMBL20338127 0.82 ALDH1A1 (0.75)
Isopropylamine SCHEMBL141429 0.82 SLC7A5 (0.44)
SCHEMBL8227653 0.82
SCHEMBL15047 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746400-A Compounds useful as selective androgen receptor modulators 南京明德新药研发有限公司 2022-07-12 CN disclosed
CN-114728904-A Bicyclic compounds as selective androgen receptor modulators 南京明德新药研发有限公司 2022-07-08 CN disclosed
EP-3057950-B1 PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T JANSSEN PHARMACEUTICA NV (BE) 2020-12-02 EP disclosed
US-10369146-B2 Phenyl linked quinolinyl modulators of RORγt JANSSEN PHARMACEUTICA NV (BE) 2019-08-06 US disclosed
US-10188653-B2 Diacylglycerol acyltransferase 2 inhibitors PFIZER INC. (US) 2019-01-29 US disclosed
EP-3119757-B1 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS FOR USE IN THE TREATMENT OF METABOLIC AND RELATED DISORDERS PFIZER (US) 2018-05-16 EP disclosed
US-20180042926-A1 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS PFIZER INC. (US) 2018-02-15 US disclosed
US-9789110-B2 Diacylglycerol acyltransferase 2 inhibitors PFIZER INC. (US) 2017-10-17 US disclosed
EP-3119757-A1 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS FOR USE IN THE TREATMENT OF METABOLIC AND RELATED DISORDERS Pfizer Inc. (US) 2017-01-25 EP disclosed
US-20160303125-A1 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS PFIZER INC. (US) 2016-10-20 US disclosed
US-9440949-B2 Diacylglycerol acyltransferase 2 inhibitors PFIZER INC. (US) 2016-09-13 US disclosed
EP-3057950-A1 PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T Janssen Pharmaceutica N.V. (BE) 2016-08-24 EP disclosed
US-9403816-B2 Phenyl linked quinolinyl modulators of RORγt JANSSEN PHARMACEUTICA NV (BE) 2016-08-02 US disclosed
WO-2015140658-A1 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS FOR USE IN THE TREATMENT OF METABOLIC AND RELATED DISORDERS PFIZER INC. (US) 2015-09-24 WO disclosed
US-20150259323-A1 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS PFIZER INC. (US) 2015-09-17 US disclosed
WO-2015057203-A1 PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T JANSSEN PHARMACEUTICA NV (BE) 2015-04-23 WO disclosed
US-20150105404-A1 PHENYL LINKED QUINOLINYL MODULATORS OF RORyt JANSSEN PHARMACEUTICA NV (BE) 2015-04-16 US disclosed
EP-2136807-B1 PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS GLAXO GROUP LTD (GB) 2010-11-03 EP disclosed
US-20100048544-A1 PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE-DERIVATIVES FOR TREATING TUBERCULOSIS GLAXO GROUP LIMITED (GB) 2010-02-25 US disclosed
US-20060041123-A1 Antibacterial agents GLAXO GROUP LIMITED (GB) 2006-02-23 US disclosed