Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000465 | 0.88 | HPGD (0.43) | GCGRHPGDNPC1MAPK1HTT | |
| SCHEMBL29925513 | 0.88 | HPGD (0.43) | GCGRHPGDNPC1MAPK1HTT | |
| SCHEMBL324414 | 0.87 | HPGD (0.43) | GCGRHPGDNPC1MAPK1HTT | |
| SCHEMBL2654884 | 0.87 | PDCD1 (0.42) | TYRGCGRHPGDNPC1MAPK1 | |
| SCHEMBL10610552 | 0.87 | GCGR (0.41) | TYRGCGRHPGDNPC1MAPK1 | |
| SCHEMBL2865287 | 0.83 | GCGR (0.44) | TYRGCGRHPGDNPC1MAPK1 | |
| SCHEMBL27701575 | 0.83 | SLC37A4 (0.50) | SLC37A4BCL2L1HSD17B10KDM4E | |
| SCHEMBL2203886 | 0.82 | GCGR (0.47) | GCGRHPGDNPC1MAPK1HTT | |
| SCHEMBL30937377 | 0.82 | GCGR (0.47) | TYRGCGRHPGDHSD11B1ALOX5 | |
| SCHEMBL1837688 | 0.81 | BCL2L1 (0.48) | GCGRHPGDNPC1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088138-B1 | Process for producing isocyanate | ASAHI KASEI CHEMICALS CORP (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-8362293-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20100069665-A1 | PROCESS FOR PRODUCING ISOCYANATES | AHAHI KASEI CHEMICALS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2088138-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2009-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069665-A1 | PROCESS FOR PRODUCING ISOCYANATES | CPS1, IDH2, PHGDH | TYR 1646/4885GCGR 1804/4885HPGD 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.