Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | REN | P00797 | 6/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | NRP1 | O14786 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215690 | 0.96 | MAPK8 (0.51) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL30658576 | 0.94 | KDM1A (0.51) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL31696335 | 0.93 | KDM1A (0.54) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL31031628 | 0.92 | MAPK8 (0.47) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL31318939 | 0.90 | MAPK8 (0.51) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL29442098 | 0.90 | KDM1A (0.47) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL31031472 | 0.90 | MAPK8 (0.47) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL31165809 | 0.90 | MAPK8 (0.45) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL7351817 | 0.89 | MAPK8 (0.41) | MAPK8MAPK9MAPK10KDM1AREN | |
| SCHEMBL7351804 | 0.89 | MAPK8 (0.41) | MAPK8MAPK9MAPK10KDM1AREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040758-A2 | BIORESPONSIVE POLYMERS | Interface Biologics Inc. (CA) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008053362-A2 | BIORESPONSIVE POLYMERS | INTERFACE BIOLOGICS, INC. (CA) | 2008-05-08 | — | — | WO | disclosed |