SCHEMBL29548952

SCHEMBL29548952

N=C(N)NCCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.48
▸ MAPK8 P45983 1/20 0.46
▸ MAPK9 P45984 1/20 0.46
▸ MAPK10 P53779 1/20 0.46
▸ MAOB P27338 1/20 0.44
▸ KDM5A P29375 1/20 0.44
▸ KDM1B Q8NB78 1/20 0.44
▸ KEAP1 Q14145 1/20 0.42
▸ NMUR2 Q9GZQ4 3/20 0.39
▸ NMUR1 Q9HB89 3/20 0.39
▸ OPRM1 P35372 6/20 0.39
▸ OPRK1 P41145 6/20 0.39
▸ EPHA2 P29317 1/20 0.38
▸ TGM2 P21980 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29855959 0.95 KDM1A (0.47) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL3215690 0.94 MAPK8 (0.51) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL29442098 0.93 KDM1A (0.47) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL7351804 0.93 MAPK8 (0.41) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL7351817 0.93 MAPK8 (0.41) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL29607893 0.92 KDM1A (0.48) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL30658576 0.92 KDM1A (0.51) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL31696335 0.90 KDM1A (0.54) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL3865485 0.89 MAPK8 (0.50) KDM1AMAPK8MAPK9MAPK10MAOB
SCHEMBL31165809 0.89 MAPK8 (0.45) KDM1AMAPK8MAPK9MAPK10MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605453-B2 CP2C-targeting peptide-based anticancer agent INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2026-04-21 — — US disclosed
US-20230078718-A1 UNSATURATED FATTY ACID-CONJUGATED CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2023-03-16 — — US disclosed
EP-4101470-A1 UNSATURATED FATTY ACID-CONJUGATED CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT Industry-University Cooperation Foundation Hanyang University (KR) 2022-12-14 — — EP disclosed
CN-115361975-A Anticancer agent based on unsaturated fatty acid conjugated CP2C targeting peptide 汉阳大学校产学协力团 2022-11-18 — — CN disclosed
EP-4005583-A1 CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT Industry - University Cooperation Foundation Hanyang University (KR) 2022-06-01 — — EP disclosed
US-20220160888-A1 CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160888-A1 CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT SREBF2, BCLAF1, CIP2A KDM1A 3703/4885MAPK8 4181/4885MAPK9 4371/4885
US-20230078718-A1 UNSATURATED FATTY ACID-CONJUGATED CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT ZDHHC2, FFAR2, SLC27A2 KDM1A 3454/4885MAPK8 2769/4885MAPK9 4053/4885
US-12605453-B2 CP2C-targeting peptide-based anticancer agent SREBF2, SLC27A2, ZDHHC2 KDM1A 598/4885MAPK8 3817/4885MAPK9 4455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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