Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991450 | 0.98 | CYP11B2 (0.40) | CYP11B2CYP11B1TRPA1CYP19A1MAOA | |
| SCHEMBL3215956 | 0.97 | CYP11B2 (0.39) | CYP11B2CYP11B1TRPA1CYP19A1MAOA | |
| SCHEMBL29172622 | 0.83 | TRPA1 (0.41) | CYP11B2CYP11B1TRPA1MAOAMAOB | |
| SCHEMBL401773 | 0.73 | TRPA1 (0.40) | CYP11B2CYP11B1TRPA1CYP19A1MAOA | |
| SCHEMBL13859949 | 0.67 | TSHR (0.35) | TRPA1CYP19A1MAOAMAOB | |
| SCHEMBL19810041 | 0.67 | CYP11B1 (0.40) | CYP11B2CYP11B1TRPA1MAOAMAOB | |
| SCHEMBL12094093 | 0.66 | HSP90AA1 (0.35) | CYP11B2CYP11B1 | |
| SCHEMBL15056698 | 0.66 | CYP11B2 (0.36) | CYP11B2CYP11B1TRPA1CYP19A1GPR84 | |
| SCHEMBL4851869 | 0.66 | TRPA1 (0.33) | CYP11B2CYP11B1TRPA1MAOAMAOB | |
| SCHEMBL30848588 | 0.65 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12005070-B2 | Protective agent for keratoconjunctiva or suppressive agent for keratoconjunctival disorder | TOYO SUGAR REFINING CO., LTD. (JP) | 2024-06-11 | — | — | US | disclosed |
| CN-111526892-B | Ophthalmic product and masking method | 狮王株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-111526892-A | Ophthalmic product and masking method | 狮王株式会社 | 2020-08-11 | — | — | CN | disclosed |
| EP-2783689-B1 | KERATOCONJUNCTIVAL PROTECTING AGENT, OR KERATOCONJUNCTIVAL DISORDER INHIBITING AGENT | TOYO SUGAR REFINING CO LTD (JP) | 2019-09-25 | — | — | EP | disclosed |
| US-20160367584-A1 | PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER | TOYO SUGAR REFINING CO., LTD. (JP) | 2016-12-22 | — | — | US | disclosed |
| US-20140315836-A1 | PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER | TOYO SUGAR REFINING CO., LTD. (JP) | 2014-10-23 | — | — | US | disclosed |
| EP-2783689-A1 | KERATOCONJUNCTIVAL PROTECTING AGENT, OR KERATOCONJUNCTIVAL DISORDER INHIBITING AGENT | Toyo Sugar Refining Co., Ltd. (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-20100069323-A1 | COMPOSITION FOR APPLICATION TO SKIN OR MUCOSA | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| CN-101534863-A | Composition for application to the skin or mucosa | ROHTO PHARMA (JP) | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160367584-A1 | PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER | UGCG, GBA1, GOLGA2 | CYP11B2 3651/4885CYP11B1 4125/4885TRPA1 3105/4885 |
| US-20140315836-A1 | PROTECTIVE AGENT FOR KERATOCONJUNCTIVA OR SUPPRESSIVE AGENT FOR KERATOCONJUNCTIVAL DISORDER | UGCG, GBA1, GOLGA2 | CYP11B2 3651/4885CYP11B1 4125/4885TRPA1 3105/4885 |
| US-12005070-B2 | Protective agent for keratoconjunctiva or suppressive agent for keratoconjunctival disorder | UGCG, GBA1, GOLGA2 | CYP11B2 3651/4885CYP11B1 4125/4885TRPA1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.