SCHEMBL321603

SCHEMBL321603

O=C(O)[C@H](CS)NCC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
NFKB1 P19838 1/20 0.44
PTGS2 P35354 1/20 0.44
THPO P40225 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 2/20 0.41
ACE P12821 1/20 0.40
FOLH1 Q04609 1/20 0.38
OR51E2 Q9H255 1/20 0.34
TGFBR1 P36897 3/20 0.34
MME P08473 2/20 0.34
PTGS1 P23219 1/20 0.32
SLC7A11 Q9UPY5 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321604 1.00 KDM4E (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL5967472 0.86 ACE (0.45) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL5967479 0.86 ACE (0.45) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL5712807 0.85 TGFBR1 (0.42) LMNAOR51E2TGFBR1MMECA1
SCHEMBL5712806 0.85 TGFBR1 (0.42) LMNAOR51E2TGFBR1MMECA1
SCHEMBL2633849 0.85 ACE (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL8974998 0.85 ACE (0.44) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL9924203 0.82 KDM4E (0.47) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL11095681 0.82 KDM4E (0.42) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4263217 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3941219-A1 SAPONIN-BASED VACCINE ADJUVANTS The UAB Research Foundation (US) 2022-01-26 EP claimed
WO-2020190959-A1 SAPONIN-BASED VACCINE ADJUVANTS THE UAB RESEARCH FOUNDATION (US) 2020-09-24 WO claimed
EP-3377099-A1 ADJUVANTING SYSTEMS AND WATER-FREE VACCINE COMPOSITIONS COMPRISING A POLYI:C POLYNUCLEOTIDE ADJUVANT AND A LIPID-BASED ADJUVANT ImmunoVaccine Technologies Inc. (CA) 2018-09-26 EP claimed
CN-108430505-A The auxiliary system of adjuvant including polyinosinic acid polynucleotides adjuvant and based on lipid and anhydrous vaccine composition 免疫疫苗技术有限公司 2018-08-21 CN claimed
EP-3174554-A1 NANOPARTICLES, METHODS OF PREPARATION, AND USES THEREOF Boehringer Ingelheim Vetmedica GmbH (DE) 2017-06-07 EP claimed
WO-2016016401-A1 NANOPARTICLES, METHODS OF PREPARATION, AND USES THEREOF BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2016-02-04 WO claimed
WO-2012078116-A1 IMMUNOGENIC CHIKUNGUNYA VIRUS PEPTIDES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-06-14 WO claimed
US-20100003275-A1 Immunostimulatory Composition comprising Lipoprotein in Microalgae Extract THE UNIVERSITY OF MISSISSIPPI (US) 2010-01-07 US claimed
EP-2064232-A2 IMMUNOSTIMULATORY COMPOSITION COMPRISING LIPOPROTEIN IN MICROALGAE EXTRACT University of Mississippi (US) 2009-06-03 EP claimed
WO-2009023714-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PROPHYLAXIS OF HYPERTENSION THYMON, LLC (US) 2009-02-19 WO claimed
WO-2008031092-A9 IMMUNOSTIMULATORY COMPOSITION COMPRISING LIPOPROTEIN IN MICROALGAE EXTRACT UNIV MISSISSIPPI (US) 2008-07-31 WO claimed
WO-2008031092-A2 IMMUNOSTIMULATORY COMPOSITION COMPRISING LIPOPROTEIN IN MICROALGAE EXTRACT UNIVERSITY OF MISSISSIPPI (US) 2008-03-13 WO claimed
CN-1326567-C Egg yolk antibody composition for preventing and treating atypical pneumonia and its preparation method GUO ZHANJUN (CN) 2007-07-18 CN claimed
CN-1559610-A Vaccine curing for disease and its preparation method 郭占军 2005-01-05 CN claimed
CN-1557487-A Immunogenicity composition for preventing and treating diseases and its preparation 郭占军 2004-12-29 CN claimed
CN-1478550-A Egg yolk antibody composition for preventing and treating atypical pneumonia and its preparation method 郭占军 2004-03-03 CN claimed
CN-1460522-A Egg yolk antibody composite for preventing and curing diseases and its preparaion method GUO ZHANJUN (CN) 2003-12-10 CN claimed
WO-1995000846-A1 DOMAIN LIGATION STRATEGY TO ENGINEER PROTEINS WITH UNUSUAL ARCHITECTURES TAM JAMES P (US) 1995-01-05 WO claimed
EP-3728289-B1 OPTIMISED COMPOUNDS Axelia Oncology Pty Ltd (AU) 2025-09-10 EP disclosed
US-4439425-A IMMUNOLOGY CIBA-GEIGY CORPORATION (US) 1984-03-27 US disclosed