Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633849 | 1.00 | ACE (0.44) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL5967472 | 0.98 | ACE (0.45) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL5967479 | 0.98 | ACE (0.45) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL321603 | 0.85 | KDM4E (0.44) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL321604 | 0.85 | KDM4E (0.44) | ACEMMEKDM4EMAPTTHRB | |
| Glycerin SCHEMBL28033837 | 0.81 | MME (0.43) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL5712807 | 0.79 | TGFBR1 (0.42) | MMETGFBR1LMNACA1CA2 | |
| SCHEMBL5712806 | 0.79 | TGFBR1 (0.42) | MMETGFBR1LMNACA1CA2 | |
| SCHEMBL2633846 | 0.79 | ACE (0.47) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL627559 | 0.77 | MME (0.48) | ACEMMEKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010583-A1 | VACCINE CONTAINING A HAEMOPROTEIN | MALLINCKRODT VETERINARY, INC. (US) | 1996-04-11 | — | — | WO | disclosed |
| EP-0703789-A1 | VACCINE CONTAINING A SERINE PROTEASE | Mallinckrodt Veterinary, Inc. (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0666919-A1 | VACCINE CONTAINING A THIOL PROTEASE | Mallinckrodt Veterinary, Inc. (US) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994028925-A1 | VACCINE CONTAINING A SERINE PROTEASE | MALLINCKRODT VETERINARY INC. (US) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994009142-A1 | VACCINE CONTAINING A THIOL PROTEASE | MALLINCKRODT VETERINARY, INC. (US) | 1994-04-28 | — | — | WO | disclosed |