SCHEMBL3216062

SCHEMBL3216062

COc1ccc2c(c1)C(C)(C)C(C)=N2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.53
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
VDR P11473 1/20 0.36
MDM2 Q00987 1/20 0.36
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
CYP3A4 P08684 1/20 0.35
NCF1 P14598 1/20 0.35
NOS3 P29474 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL11866816 0.98 EHMT2 (0.51) EHMT2CA12CA1CA2CA7
Hydrochloric Acid SCHEMBL17824011 0.98 EHMT2 (0.51) EHMT2CA12CA1CA2CA7
SCHEMBL10126936 0.86 EHMT2 (0.42) EHMT2CA12CA1CA2CA7
SCHEMBL5850339 0.84 EHMT2 (0.40) EHMT2MEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL5850332 0.83 CYP1A1 (0.50) EHMT2CA12CA1CA2CA7
SCHEMBL11291373 0.81 MAPT (0.41) EHMT2MEN1KMT2AKDM4EALDH1A1
SCHEMBL11221570 0.80 TDP1 (0.40) EHMT2MEN1KMT2AKDM4EALDH1A1
SCHEMBL101495 0.80 EHMT2 (0.35) EHMT2MEN1KMT2A
SCHEMBL28562034 0.80 EHMT2 (0.48) EHMT2KMT2AALDH1A1PDE3BPDE3A
SCHEMBL11848693 0.79 CYP1A2 (0.40) LMNASMN1; SMN2PDE3BPDE3ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970746-B N-hybrid porphyrin-dipyrrolene photoacoustic developer and synthesis method thereof 三峡大学 2021-08-24 CN claimed
CN-111606915-B Preparation method of spiropyran photochromic material 浙大宁波理工学院 2021-06-15 CN claimed
CN-111606915-A Preparation method of spiropyran photochromic material 浙大宁波理工学院 2020-09-01 CN claimed
US-4062865-A Process for the synthesis of substituted indolenines SNAMPROGETTI S.P.A. (IT) 1977-12-13 US claimed
JP-4187687-A None JP disclosed
CN-122036584-A Fluorescent dye compound and preparation method and application thereof 深圳大学 2026-05-15 CN disclosed
US-12595281-B2 Indodicarbocyanine phosphoramidites with bathochromically shifted absorption and emission, and tunable hydrophobicity THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2026-04-07 US disclosed
US-20260077067-A1 IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS UNIV DUNDEE (GB) 2026-03-19 US disclosed
US-12496361-B2 Imaging compounds for detecting or imaging senescent cells UNIVERSITY OF DUNDEE (GB) 2025-12-16 US disclosed
EP-4649113-A1 IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS University Of Dundee (GB) 2025-11-19 EP disclosed
US-20250114483-A1 IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS UNIVERSITY OF DUNDEE (GB) 2025-04-10 US disclosed
WO-2024149992-A1 IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS UNIVERSITY OF DUNDEE (GB) 2024-07-18 WO disclosed
US-4281112-A Process for the preparation of cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-07-28 US disclosed
US-4255333-A THERMAL ENOLIZATION OF A SCHIFF BASE FOLLOWED BY CYCLIZATION USING AN ACID CATALYST BASF AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed
EP-0023671-A1 Process for the preparation of cationic dyestuffs BAYER AG (DE) 1981-02-11 EP disclosed
EP-0003556-A1 Process for the synthesis of indolenines BASF Aktiengesellschaft (DE) 1979-08-22 EP disclosed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US disclosed
US-4139274-A Apparatus for changing color MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-02-13 US disclosed
US-4110070-A QUATERNIZING INDOLENINE METHINE COMPOUND ON FIBERS TO FORM CATIONIC DYE HODOGAYA CHEMICAL CO., LTD. (JP) 1978-08-29 US disclosed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077067-A1 IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS NR0B1, NR4A3, NCOA4 EHMT2 4667/4885CA12 2960/4885CA1 2900/4885
US-12595281-B2 Indodicarbocyanine phosphoramidites with bathochromically shifted absorption and emission, and tunable hydrophobicity DNMT1, DNMT3A, INCENP EHMT2 624/4885CA12 1741/4885CA1 4369/4885
US-12496361-B2 Imaging compounds for detecting or imaging senescent cells LIMS1, GLA, TP53 EHMT2 4701/4885CA12 2773/4885CA1 2797/4885
US-20250114483-A1 IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS LIMS1, GLA, TP53 EHMT2 4701/4885CA12 2773/4885CA1 2797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.