SCHEMBL101495

SCHEMBL101495

CC1=Nc2ccc(OC=O)cc2C1(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
STS P08842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3216062 0.80 EHMT2 (0.53) EHMT2MEN1KMT2A
Hydrochloric Acid SCHEMBL17824011 0.79 EHMT2 (0.51) EHMT2MEN1KMT2A
SCHEMBL11291373 0.76 MAPT (0.41) EHMT2MEN1KMT2A
SCHEMBL11221570 0.75 TDP1 (0.40) EHMT2MEN1KMT2A
SCHEMBL11848693 0.74 CYP1A2 (0.40)
SCHEMBL10111540 0.73 STS (0.31) STS
SCHEMBL38660687 0.72 TDP1 (0.41) MEN1KMT2A
SCHEMBL31142498 0.71 PLA2G2A (0.39)
SCHEMBL25336502 0.71 PDE3B (0.45)
SCHEMBL16378373 0.70 MEN1 (0.37) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920365-B2 Functionalized cyanine dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2018-03-20 US disclosed
US-20170183501-A1 Cyanine Dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2017-06-29 US disclosed
US-9441270-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-09-13 US disclosed
US-20150344950-A1 Functionalized Cyanine Dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-12-03 US disclosed
US-9051263-B2 Functionalized cyanine dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-06-09 US disclosed
US-20150072894-A1 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-03-12 US disclosed
US-8889886-B2 Cyanine dyes PACIFIC BIOSCIENCES, INC. (US) 2014-11-18 US disclosed
US-8722905-B2 Dyes and photoelectric conversion devices containing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-05-13 US disclosed
US-8669374-B2 Functionalized cyanine dyes (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2014-03-11 US disclosed
US-8637680-B2 Dye-sensitized solar cell, photoelectric conversion element, and dye for use in the solar cell and the element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-01-28 US disclosed
US-20130261314-A1 DYES AND PHOTOELECTRIC CONVERSION DEVICES CONTAINING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-10-03 US disclosed
US-20120058469-A1 FUNCTIONALIZED CYANINE DYES (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 US disclosed
US-20120058482-A1 FUNCTIONALIZED CYANINE DYES (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 US disclosed
US-20120052506-A1 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-01 US disclosed
US-20120029206-A1 DYE-SENSITIZED SOLAR CELL, PHOTOELECTRIC CONVERSION ELEMENT, AND DYE FOR USE IN THE SOLAR CELL AND THE ELEMENT NATIONAL UNIVERSITY CORPORATION KYUSHU INSTITUTE OF TECHNOLOGY (JP) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029206-A1 DYE-SENSITIZED SOLAR CELL, PHOTOELECTRIC CONVERSION ELEMENT, AND DYE FOR USE IN THE SOLAR CELL AND THE ELEMENT CRY1, CRY2, SQLE EHMT2 1320/4885MEN1 2055/4885KMT2A 2820/4885
US-20120052506-A1 CYANINE DYES ABCG2, IK, ACR EHMT2 3164/4885MEN1 2288/4885KMT2A 2564/4885
US-20120058482-A1 FUNCTIONALIZED CYANINE DYES (PEG) ACR, IK, EGFR EHMT2 3738/4885MEN1 3947/4885KMT2A 3543/4885
US-20130261314-A1 DYES AND PHOTOELECTRIC CONVERSION DEVICES CONTAINING THE SAME CRY2, CRY1, PRDX1 EHMT2 554/4885MEN1 1765/4885KMT2A 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.