Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945740 | 1.00 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL8945623 | 1.00 | LMNA (0.63) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL8154447 | 0.98 | LMNA (0.60) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL9095817 | 0.92 | LMNA (0.52) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL31112799 | 0.87 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL31112945 | 0.87 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL31112808 | 0.87 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL8346746 | 0.84 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL8769110 | 0.84 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL28289715 | 0.84 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2077987-B1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | TRANSTECH PHARMA INC (US) | 2010-11-24 | — | — | EP | disclosed |
| US-20100036150-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | TRANSTECH PHARMA, INC. | 2010-02-11 | — | — | US | disclosed |
| EP-2077987-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | Transtech Pharma, Inc. (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008051563-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | TRANSTECH PHARMA, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| US-6045720-A | EXHIBITS A FERROELECTRIC LIQUID CRYSTALLINE PHASE AND AN ANTIFERROELECTRIC LIQUID CRYSTALLINE PHASE BY ITSELF; HIGH SPEED RESPONSE; DISPLAY ELEMENT; OPTICAL SWITCHING ELEMENT; | CHISSO CORPORATION (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0774452-B1 | Optically active compounds having plural chiral centers and the production thereof | CHISSO CORP (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0428392-B1 | Processes for the preparation of optically active compounds having plural chiral centers | CHISSO CORP (JP) | 1998-05-27 | — | — | EP | disclosed |
| EP-0454463-B1 | Process for producing epoxyalcohols of high optical purity | ARCO CHEM TECH (US) | 1997-08-13 | — | — | EP | disclosed |
| EP-0774452-A1 | Optically active compounds having plural chiral centers and the production thereof | Chisso Corporation (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5574182-A | HYDROLYSING 3-HYDROXYCARBOXYLIC ACID, CYCLIZING ESTER TO FORM 1,3-DIOXAN-4-ONE, DECYCLIZATION AND ESTERIFICATION | CHISSO CORPORATION (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0454463-A2 | Process for producing epoxyalcohols of high optical purity | ARCO Chemical Technology, L.P. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0428392-A2 | Optically active compounds having plural chiral centers and the production thereof | Chisso Corporation (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4971909-A | TRANSESTERIFICATION IN THE PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4962031-A | SPECIFIC COMPOUNDS HAVING HYDROXYL GROUPS REACTED WITH ESTERS IN PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4916074-A | ENZYMATIC TRANS ESTERIFICATION OF ALCOHOL WITH TRIGLYCERIDES; PSEUDOMONAS-DERIVED ENZYME | CHISSO CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |
| US-4882451-A | SILYL ALCOHOLS OR ESTERS | CHISSO CORPORATION (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0304706-A2 | Process for producing optically active compounds having pyridine skeletons | CHISSO CORPORATION (JP) | 1989-03-01 | — | — | EP | disclosed |
| EP-0290878-A2 | Optically active compounds and process for producing thereof | Chisso Corporation (JP) | 1988-11-17 | — | — | EP | disclosed |
| EP-0288994-A2 | Process for producing optically active compounds | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |
| EP-0266217-A2 | Process for producing optically active compounds | CHISSO CORPORATION (JP) | 1988-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036150-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | CYP8B1, CYP51A1, COMT | LMNA 1188/4885MAPT 2796/4885MAPK1 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.