SCHEMBL8769110

SCHEMBL8769110

CCCCCCCCCCCCCCCCCC(=O)OC(Cl)Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.68
MAPT P10636 3/20 0.63
MAPK1 P28482 3/20 0.63
ALDH1A1 P00352 2/20 0.59
DGKA P23743 1/20 0.55
PRKCA P17252 1/20 0.54
PRKCE Q02156 1/20 0.54
PRKCQ Q04759 1/20 0.54
PRKCD Q05655 1/20 0.54
CYP1A2 P05177 2/20 0.50
PAM P19021 2/20 0.50
TSHR P16473 2/20 0.50
MEN1 O00255 1/20 0.50
GMNN O75496 1/20 0.50
HSP90AA1 P07900 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
NR1H4 Q96RI1 1/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8346746 1.00 LMNA (0.68) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL28289715 1.00 LMNA (0.68) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL27909979 0.89 PRKCA (0.61) LMNAMAPTALDH1A1DGKAPRKCA
SCHEMBL15270660 0.89 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL15271162 0.89 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL15270500 0.89 LMNA (0.50) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL15270812 0.87 LMNA (0.46) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL10714635 0.86 LMNA (0.71) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL9446900 0.86 LMNA (0.71) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL31112584 0.86 LMNA (0.71) LMNAMAPTMAPK1ALDH1A1DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848685-B Preparation method of amphiphilic PN = PS type phosphorus-containing tree crown macromolecule nano micelle and application of drug carrier of amphiphilic PN = PS type phosphorus-containing tree crown macromolecule nano micelle 东华大学 2021-08-31 CN disclosed
CN-111848685-A Preparation method of amphiphilic PN = PS type phosphorus-containing tree crown macromolecule nano micelle and application of drug carrier of amphiphilic PN = PS type phosphorus-containing tree crown macromolecule nano micelle 东华大学 2020-10-30 CN disclosed
EP-0492590-B1 Photopolymerizable composition and dry PS plate FUJI PHOTO FILM CO LTD (JP) 1997-09-10 EP disclosed
US-5603926-A CONTAINS A (METH)ACRYLIC MONOMER HAVING AN AMINO GROUP OSAKA YUKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-02-18 US disclosed
US-5334486-A Reaction product of glycidyl methacrylate and a polyamine; photopolymerization initiator FUJI PHOTO FILM CO., LTD. (JP) 1994-08-02 US disclosed
WO-1992020736-A1 POLYMER BASED SELFLUBRICATING COMPOSITE SHIAO SHIN JEN (CN) 1992-11-26 WO disclosed
EP-0492590-A1 Photopolymerizable composition and dry PS plate Fuji Photo Film Co., Ltd. (JP) 1992-07-01 EP disclosed
CN-1036976-A Radiation curing printing ink and coating composition that wherein contained initiator is an ionic dye compounds MEAD CORP (US) 1989-11-08 CN disclosed
EP-0301769-A2 Radiation-curable compositions and their use for printing and coating THE MEAD CORPORATION (US) 1989-02-01 EP disclosed
US-4751102-A FOR PHOTOHARDENABLE FREE RADICAL ADDITION POLYMERIZABLE OR CROSSLINKABLE COMPOUND THE MEAD CORPORATION (US) 1988-06-14 US disclosed
US-4037021-A Photopolymerizable compositions containing a keto dioxolane as the photosensitizer SUN CHEMICAL CORPORATION (US) 1977-07-19 US disclosed
US-4028204-A Photopolymerizable compounds and compositions comprising the product of the reaction of a resin and a polycarboxy-substituted benzophenone SUN CHEMICAL CORPORATION (US) 1977-06-07 US disclosed
US-4022674-A Photopolymerizable compounds and compositions comprising the product of the reaction of a monomeric ester and a polycarboxy-substituted benzophenone SUN CHEMICAL CORPORATION (US) 1977-05-10 US disclosed
US-4008138-A Photopolymerizable compounds and compositions comprising the product of the reaction of a monocarboxy-substituted benzophenone with a resin SUN CHEMICAL CORPORATION (US) 1977-02-15 US disclosed
US-4004998-A Photopolymerizable compounds and compositions comprising the product of the reaction of a hydroxy-containing ester and a monocarboxy-substituted benzophenone SUN CHEMICAL CORPORATION (US) 1977-01-25 US disclosed
US-3992363-A POLY(TRICHLOROACETYL-STYRENE) SUN CHEMICAL CORPORATION (US) 1976-11-16 US disclosed
US-3978133-A UNSATURATED MONOMERS, POLYHALOACETYL SUN CHEMICAL CORPORATION (US) 1976-08-31 US disclosed
US-3966573-A HALOGENATED HYDROCARBONS, CARBONYL COMPOUNDS, ORGANO-NITROGEN, PHOSPHOROUS, ARSENIC, BISMUTH, OR ANTIMONY COMPOUNDS SUN CHEMICAL CORPORATION (US) 1976-06-29 US disclosed
US-3944509-A UNSATURATED, PHOTOPOLYMERIZABLE MONOMERS SUN CHEMICAL CORPORATION (US) 1976-03-16 US disclosed
US-3933682-A Photopolymerization co-initiator systems SUN CHEMICAL CORPORATION (US) 1976-01-20 US disclosed