SCHEMBL3217019

SCHEMBL3217019

O=c1ccc2cc3c4c(c2o1)C=CCN4CC=C3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.40
▸ ALDH1A1 P00352 5/20 0.40
▸ TDP1 Q9NUW8 4/20 0.40
▸ LMNA P02545 4/20 0.40
▸ MAPT P10636 4/20 0.40
▸ GAA P10253 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ USP2 O75604 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ TLR9 Q9NR96 1/20 0.40
▸ PDE4D Q08499 3/20 0.36
▸ MGAM O43451 1/20 0.36
▸ SI P14410 1/20 0.36
▸ MGAM2 Q2M2H8 1/20 0.36
▸ MCL1 Q07820 6/20 0.35
▸ HPGD P15428 4/20 0.35
▸ HSD17B10 Q99714 4/20 0.35
▸ ALOX15 P16050 3/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30697920 1.00 KDM4E (0.40) KDM4EALDH1A1TDP1LMNAMAPT
Hydrochloric Acid SCHEMBL22616816 0.99 KDM4E (0.39) KDM4EALDH1A1TDP1LMNAMAPT
SCHEMBL28564674 0.78 ALDH1A1 (0.63) KDM4EALDH1A1TDP1LMNAMAPT
SCHEMBL4302891 0.73 KDM4E (0.40) KDM4EALDH1A1TDP1LMNAMAPT
SCHEMBL23845864 0.65 GAA (0.38) KDM4EALDH1A1TDP1LMNAMAPT
SCHEMBL18244163 0.64 — —
SCHEMBL23418398 0.64 KDM4E (0.42) KDM4EALDH1A1TDP1LMNAMAPT
SCHEMBL30301203 0.63 — —
SCHEMBL29207958 0.62 CYP1A2 (0.58) KDM4EALDH1A1TDP1LMNAMAPT
SCHEMBL24788182 0.59 CA9 (0.47) KDM4EALDH1A1TDP1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114133387-A Fluorescent probe with viscosity sensing property and capable of targeting multiple organelles 郑州大学 2022-03-04 — — CN claimed
US-20040264528-A1 External cavity organic laser CITICORP NORTH AMERICA, INC., AS AGENT 2004-12-30 — — US claimed
CN-117590691-A Photosensitive resin composition 中央硝子株式会社 2024-02-23 — — CN disclosed
CN-117311090-A Photosensitive resin composition 中央硝子株式会社 2023-12-29 — — CN disclosed
CN-116508415-A Light-emitting display device 乐金显示有限公司 2023-07-28 — — CN disclosed
CN-115583912-A Carbazole-containing aromatic amine compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2023-01-10 — — CN disclosed
CN-115448870-A Arylamine compound containing carbazole group and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2022-12-09 — — CN disclosed
CN-113383438-B Organic electroluminescent element 索路思高新材料有限公司 2022-11-01 — — CN disclosed
CN-113501812-B Triarylamine compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2022-10-14 — — CN disclosed
CN-113270554-A Organic light emitting display device 三星显示有限公司 2021-08-17 — — CN disclosed
US-20210221903-A1 BCMA-TARGETING CHIMERIC ANTIGEN RECEPTOR AND USES THEREOF HRAIN BIOTECHNOLOGY CO., LTD. (CN) 2021-07-22 — — US disclosed
US-20080194522-A1 Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE 2008-08-14 — — US disclosed
EP-1914741-A2 Optical pickup apparatus and optical reproducing method Funai Electric Co., Ltd. (JP) 2008-04-23 — — EP disclosed
EP-1912209-A1 Optical recording medium, recording method of information on optical recording medium and reproducing method thereof Funai Electric Co., Ltd. (JP) 2008-04-16 — — EP disclosed
CN-101162596-A Optical recording medium, recording method of information on optical recording medium and reproducing method thereof FUNAI ELECTRIC CO (JP) 2008-04-16 — — CN disclosed
CN-101162592-A Optical pickup apparatus and optical reproducing method FUNAI ELECTRIC CO (JP) 2008-04-16 — — CN disclosed
US-20080084806-A1 Optical recording medium, recording method of information on optical recording medium and reproducing method thereof FUNAI ELECTRIC CO., LTD. (JP) 2008-04-10 — — US disclosed
WO-2006023821-A2 LIGANDS FOR ALDOKETOREDUCTASES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2006-03-02 — — WO disclosed
US-20050009946-A1 Radical polymerization catalyst and adhesive kit for dental use TOKUYAMA CORPORATION (JP) 2005-01-13 — — US disclosed
US-20040246201-A1 OLED display and pixel structure thereof AU OPTRONICS CORP. (TW) 2004-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194522-A1 Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) MAOA, MAOB, COMT KDM4E 1183/4885ALDH1A1 181/4885TDP1 557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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