SCHEMBL321750

SCHEMBL321750

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nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.58
LMNA P02545 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.33
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27516225 1.00 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL92769 1.00 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL4422883 1.00 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
Ammonia Solution, Strong SCHEMBL27782446 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Hydrochloric Acid SCHEMBL27659069 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Methane SCHEMBL28111172 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Bromide SCHEMBL27760150 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL6514261 0.93 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL26605110 0.93 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL626497 0.93 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1090 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119242765-A Use of fucosidase 广东省科学院生物与医学工程研究所 2025-01-03 CN claimed
CN-118675657-A FDG drug synthesis optimization control method 青岛原子高通医药有限公司 2024-09-20 CN claimed
CN-116789679-A Cycloicaritin 5-glycosylation derivative and preparation method and application thereof 遵义医科大学 2023-09-22 CN claimed
CN-113444703-B Glycosyltransferase mutant for catalyzing sugar chain extension and application thereof 生合万物(苏州)生物科技有限公司 2023-09-01 CN claimed
CN-116589522-A Oleanolic acid C28 glucose trimer derivative and application thereof 昆明理工大学 2023-08-15 CN claimed
WO-2023011639-A1 OLIGOSACCHARIDE LINKER AND SIDE-CHAIN HYDROPHILIC FRAGMENT COMBINED GLYCOSITE-SPECIFIC ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院上海药物研究所 2023-02-09 WO claimed
CN-112760301-B Glycosyl transferase mutant with improved catalytic activity and application thereof 中国科学院天津工业生物技术研究所 2023-01-17 CN claimed
CN-115374593-A CO (carbon monoxide) 2 Molecular dynamics simulation method for throughput of entrainer composite system 西安石油大学 2022-11-22 CN claimed
CN-114573648-A Cannabinoid glycosides and methods of making the same 云南汉盟制药有限公司 2022-06-03 CN claimed
CN-112341506-B Acetyl glucose thiadiazole benzamide compound and synthesis method and application thereof 铜仁学院 2022-05-06 CN claimed
CN-101037842-A Low-temperature scouring and bleaching agent and preparation method thereof and preprocessing technique SHANGHAI QIRUI TEXTILE CHEMICA (CN) 2007-09-19 CN claimed
CN-101003556-A Derivative of 10 - hydroxyl camptothecin, prepartion of its liposome, and preparation method LIU XIANGHUA (CN) 2007-07-25 CN claimed
CN-1290831-C Solid generating agent for preparing peroxyacetic acid ZHEJIANG JINKE CHEMICALS CO LT (CN) 2006-12-20 CN claimed
CN-1668561-A Remedy TAKARA BIO INC (JP) 2005-09-14 CN claimed
CN-1542000-A Solid generating agent for preparing peroxyacetic acid 浙江金科化工有限公司 2004-11-03 CN claimed
EP-0956000-A4 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF UNIV EMORY (US) 2004-06-09 EP claimed
US-6071532-A SYNTHETIC VACCINES; IMMUNOLOGY; MEDICAL DIAGNOSIS EMORY UNIVERSITY (US) 2000-06-06 US claimed
EP-0956000-A1 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF EMORY UNIVERSITY (US) 1999-11-17 EP claimed
WO-1998016198-A1 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF EMORY UNIVERSITY (US) 1998-04-23 WO claimed
US-4093796-A FUNGICIDES POLITECHNIKA GDANSKA (PO) 1978-06-06 US claimed