SCHEMBL6514261

SCHEMBL6514261

CC(=O)C(=O)[C@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.48
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.43
USP2 O75604 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
KDM4E B2RXH2 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL626497 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL26605110 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
Bromide SCHEMBL28835821 0.98 PDE4A (0.46) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL27516225 0.93 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL92769 0.93 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL4422883 0.93 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL321750 0.93 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL29250362 0.92 PDE4A (0.42) PDE4ALMNAL3MBTL1TDP1USP2
Methane SCHEMBL28111172 0.91 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Bromide SCHEMBL27760150 0.91 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420693-A 6- (Isopropyl disulfide) -guanosine compound, and preparation method and application thereof 浙江大学金华研究院 2024-08-02 CN claimed
CN-114276393-A Preparation process of beta-nicotinamide riboside chloride 南京诺云生物科技有限公司 2022-04-05 CN claimed
CN-118420693-A 6- (Isopropyl disulfide) -guanosine compound, and preparation method and application thereof 浙江大学金华研究院 2024-08-02 CN disclosed
CN-117940567-A Antisense compounds that modulate the expression of WFDC2 克迈恩有限公司 2024-04-26 CN disclosed
CN-113755415-B Novel recombinant microorganism with NMN synthesis path and production method thereof 苏州华赛生物工程技术有限公司 2024-03-29 CN disclosed
CN-113755413-B Recombinant microorganism for producing beta-nicotinamide mononucleotide and method for producing NMN by using same 苏州华赛生物工程技术有限公司 2023-09-05 CN disclosed
CN-114807078-B Method for biosynthesis of NMN 四川盈嘉合生科技有限公司 2023-09-01 CN disclosed
CN-113755411-B Recombinant microorganism for high-yield of beta-nicotinamide mononucleotide and method for producing beta-nicotinamide mononucleotide by recombinant microorganism 苏州华赛生物工程技术有限公司 2023-08-01 CN disclosed
CN-112961890-B Enzymatic synthesis method of nicotinamide mononucleotide 深圳希吉亚生物技术有限公司 2023-06-27 CN disclosed
CN-111676204-B Nicotinamide phosphoribosyl transferase for preparing nicotinamide mononucleotide, coding gene, vector and application 成都及禾生物科技有限公司 2023-05-23 CN disclosed
CN-110590879-B Acridinone derivatives containing ribose or deoxyribose sugar structure and preparation method and application thereof 河南师范大学 2022-12-27 CN disclosed
CN-113755413-A Recombinant microorganism producing beta-nicotinamide mononucleotide and method for producing NMN (N-methyl-N) by using same 苏州华赛生物工程技术有限公司 2021-12-07 CN disclosed
CN-113106080-A Nicotinamide phosphoribosyl transferase mutant and application thereof 深圳希吉亚生物技术有限公司 2021-07-13 CN disclosed
CN-112961890-A Enzymatic synthesis method of nicotinamide mononucleotide 深圳希吉亚生物技术有限公司 2021-06-15 CN disclosed
CN-112608910-A Nicotinamide ribokinase and application thereof 深圳希吉亚生物技术有限公司 2021-04-06 CN disclosed
CN-111676204-A Nicotinamide phosphoribosyl transferase for preparing nicotinamide mononucleotide, coding gene, carrier and application 成都及禾生物科技有限公司 2020-09-18 CN disclosed
CN-109666658-B Nicotinamide phosphoribosyl transferase for preparing NMN, coding gene, recombinant vector and application 成都及禾生物科技有限公司 2020-08-04 CN disclosed
WO-2005016878-A2 METHODS FOR THE PREPARATION OF 5-FLUORO-PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 2005-02-24 WO disclosed
WO-2002038579-A1 COMPOSITIONS AND METHODS FOR IDENTIFYING AGENTS WHICH REGULATE CHROMOSOMAL STABILITY, GENE ACTIVATION AND AGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2002-05-16 WO disclosed
WO-1994021658-A1 ANTIVIRAL IMIDAZOLINONE NUCLEOSIDE DERIVATIVES KALMAN THOMAS I (US) 1994-09-29 WO disclosed