SCHEMBL92769

SCHEMBL92769

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nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.58
LMNA P02545 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.33
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27516225 1.00 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL4422883 1.00 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL321750 1.00 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
Ammonia Solution, Strong SCHEMBL27782446 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Hydrochloric Acid SCHEMBL27659069 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Methane SCHEMBL28111172 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
Bromide SCHEMBL27760150 0.98 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL6514261 0.93 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL26605110 0.93 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL626497 0.93 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063535-A Modified nucleoside containing amino derivative structure, oligonucleotide compound and synthesis method 北京安龙生物医药有限公司 2024-05-24 CN claimed
CN-116789679-A Cycloicaritin 5-glycosylation derivative and preparation method and application thereof 遵义医科大学 2023-09-22 CN claimed
CN-114085256-A Beta-galactosidase response carbohydrate derivative and application thereof 江南大学 2022-02-25 CN claimed
CN-113416219-A Glycosyl spiropyran compound and application thereof 华东理工大学 2021-09-21 CN claimed
CN-112625075-A alpha-L-fucosidase detection probe and preparation method and application thereof 华东理工大学 2021-04-09 CN claimed
CN-110101684-A A kind of cellular membrane biomimetic nano particle and its preparation method and application of bio-orthogonal targeting 深圳先进技术研究院 2019-08-09 CN claimed
CN-109952107-A Lin28a activators and uses thereof TES控股股份有限公司 2019-06-28 CN claimed
CN-109239372-A Abo blood group antigen detectability verifies product and its application 上海市血液中心 2019-01-18 CN claimed
CN-109072273-A Method for regulating protein galactosylation profile of recombinant protein by using holo-acetyl galactose 阿雷斯贸易股份有限公司 2018-12-21 CN claimed
CN-108822171-A A kind of anthraquinone and triazole antibiotic nucleoside analog, synthetic method and its preparing the application in antitumor or antiviral drugs 河南师范大学 2018-11-16 CN claimed
US-20070129316-A1 MUSCLE-STRENGTHENING DRUGS AND ANTI-INFLAMMATORY DRUGS DAICHO KIKAKU INCORPORATED COMPANY (JP) 2007-06-07 US claimed
WO-2004094445-A1 A MORE STABLE ANALOG OF ISO-PROPYLTHIOGALACTOSIDE FOR INDUCTION OF PROTEIN EXPRESSION IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) 2004-11-04 WO claimed
EP-0956000-A4 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF UNIV EMORY (US) 2004-06-09 EP claimed
US-6071532-A SYNTHETIC VACCINES; IMMUNOLOGY; MEDICAL DIAGNOSIS EMORY UNIVERSITY (US) 2000-06-06 US claimed
EP-0956000-A1 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF EMORY UNIVERSITY (US) 1999-11-17 EP claimed
EP-0946581-A1 THERAPEUTIC COMPOUNDS Oxford GlycoSciences (UK) Limited (GB) 1999-10-06 EP claimed
WO-1998028318-A1 THERAPEUTIC COMPOUNDS OXFORD GLYCOSCIENCES (UK) LIMITED (GB) 1998-07-02 WO claimed
WO-1998016198-A1 SYNTHESIS OF GLYCOPHOSPHOLIPID AND PEPTIDE-PHOSPHOLIPID CONJUGATES AND USES THEREOF EMORY UNIVERSITY (US) 1998-04-23 WO claimed
EP-0762884-A1 MODULATORS OF PNEUMOCOCCAL ADHESION TO CELLULAR TARGETS INVOLVING THE PLATELET ACTIVATING FACTOR RECEPTOR, AND USES THEREOF THE ROCKEFELLER UNIVERSITY (US) 1997-03-19 EP claimed
WO-1995035112-A2 MODULATORS OF PNEUMOCOCCAL ADHESION TO CELLULAR TARGETS INVOLVING THE PLATELET ACTIVATING FACTOR RECEPTOR, AND USES THEREOF THE ROCKEFELLER UNIVERSITY (US) 1995-12-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129316-A1 MUSCLE-STRENGTHENING DRUGS AND ANTI-INFLAMMATORY DRUGS CYP27A1, ACHE, MYLK PDE4A 3446/4885LMNA 829/4885L3MBTL1 4393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.