Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321963 | 0.91 | KDM5A (0.54) | KDM5AKDM5BMEN1KMT2AALDH1A1 | |
| SCHEMBL321280 | 0.82 | USP2 (0.44) | KDM5AKDM5BUSP2MEN1KMT2A | |
| SCHEMBL322275 | 0.82 | USP2 (0.44) | KDM5AKDM5BUSP2MEN1KMT2A | |
| SCHEMBL2482875 | 0.80 | KDM4E (0.52) | USP2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7754982 | 0.79 | KDM5A (0.52) | KDM5AKDM5BMEN1KMT2AALDH1A1 | |
| SCHEMBL7754979 | 0.77 | KDM5A (0.53) | KDM5AKDM5BMEN1KMT2AALDH1A1 | |
| SCHEMBL1033018 | 0.77 | KDM5A (0.53) | KDM5AKDM5BMEN1KMT2AALDH1A1 | |
| SCHEMBL321543 | 0.76 | MEN1 (0.45) | KDM5AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7861387 | 0.74 | KDM5A (0.50) | KDM5AKDM5BMEN1KMT2AALDH1A1 | |
| SCHEMBL321442 | 0.74 | MEN1 (0.45) | KDM5AKDM5BMEN1KMT2AMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590949-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | Active Biotech AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004338-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2012-01-12 | — | — | WO | disclosed |