Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322275 | 0.88 | USP2 (0.44) | KDM5AKDM5BALDH1A1MEN1KMT2A | |
| SCHEMBL7828505 | 0.86 | KDM5A (0.48) | KDM5AKDM5BMAP3K5LMNAALDH1A1 | |
| SCHEMBL321963 | 0.85 | KDM5A (0.54) | KDM5AKDM5BMAP3K5LMNAALDH1A1 | |
| SCHEMBL7826753 | 0.84 | KDM4E (0.38) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7754979 | 0.84 | KDM5A (0.53) | KDM5AKDM5BMAP3K5LMNAALDH1A1 | |
| SCHEMBL1033018 | 0.84 | KDM5A (0.53) | KDM5AKDM5BMAP3K5LMNAALDH1A1 | |
| SCHEMBL7861387 | 0.81 | KDM5A (0.50) | KDM5AKDM5BMAP3K5LMNAALDH1A1 | |
| SCHEMBL321856 | 0.79 | KDM5A (0.44) | KDM5AKDM5BMAP3K5LMNAALDH1A1 | |
| SCHEMBL7556725 | 0.78 | KMT2A (0.43) | KDM5AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16029767 | 0.76 | MAP3K5 (0.60) | KDM5AKDM5BMAP3K5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095021-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| EP-1073639-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-02-07 | — | — | EP | disclosed |
| WO-2000003991-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999055678-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 1999-11-04 | — | — | WO | disclosed |