Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754982 | 0.88 | KDM5A (0.52) | MEN1KMT2AKDM4EALDH1A1KDM5A | |
| SCHEMBL7826753 | 0.88 | KDM4E (0.38) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL321280 | 0.84 | USP2 (0.44) | USP2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2482875 | 0.82 | KDM4E (0.52) | USP2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL321856 | 0.82 | KDM5A (0.44) | USP2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4648517 | 0.78 | USP2 (0.44) | USP2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3981085 | 0.77 | MEN1 (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7556725 | 0.76 | KMT2A (0.43) | USP2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14335867 | 0.76 | USP2 (0.44) | USP2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7828560 | 0.75 | GPBAR1 (0.40) | MEN1KMT2AKDM4EAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590949-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | Active Biotech AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004338-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2012-01-12 | — | — | WO | disclosed |