Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 8/20 | 0.67 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210140 | 0.91 | GPR52 (0.80) | GPR52MMP13PTGER4 | |
| SCHEMBL3206470 | 0.89 | GPR52 (0.81) | GPR52PTGER4 | |
| SCHEMBL3219255 | 0.87 | GPR52 (0.66) | GPR52PTGER4KDM4C | |
| SCHEMBL3216166 | 0.86 | GPR52 (0.61) | GPR52PTGER4SCD5LMNA | |
| SCHEMBL1856279 | 0.86 | GPR52 (0.77) | GPR52PTGER4KDM4C | |
| SCHEMBL3204342 | 0.85 | GPR52 (0.68) | GPR52PTGER4 | |
| SCHEMBL1854239 | 0.84 | GPR52 (0.63) | GPR52MMP13PTGER4KDM4C | |
| SCHEMBL1851641 | 0.83 | GPR52 (0.62) | GPR52MMP13PTGER4SCD5KDM4C | |
| SCHEMBL1850188 | 0.80 | GPR52 (0.59) | GPR52MMP13PTGER4KDM4C | |
| SCHEMBL3207056 | 0.80 | GPR52 (1.00) | GPR52PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885MMP13 4627/4885PTGER4 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.