SCHEMBL589902

SCHEMBL589902

C=CC=CC(C(=O)O)=C(C)C=Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
HDAC3 O15379 3/20 0.46
HDAC4 P56524 3/20 0.46
HDAC1 Q13547 3/20 0.46
HDAC2 Q92769 3/20 0.46
HDAC8 Q9BY41 3/20 0.46
HDAC6 Q9UBN7 3/20 0.46
PLIN1 O60240 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 2/20 0.46
PLIN5 Q00G26 2/20 0.46
ABHD5 Q8WTS1 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HDAC7 Q8WUI4 2/20 0.46
HDAC10 Q969S8 2/20 0.46
HDAC11 Q96DB2 2/20 0.46
HDAC9 Q9UKV0 2/20 0.46
HDAC5 Q9UQL6 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3970920 0.82 HDAC3 (0.60) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL10455743 0.79 TDP1 (0.43) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL5161450 0.78 GLA (0.51) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL10231123 0.78 GLA (0.46) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL321987 0.77 GLA (0.50) GLATDP1HDAC3HDAC4HDAC1
Acetone SCHEMBL10911886 0.76 GLA (0.55) GLATDP1HDAC3HDAC4HDAC1
Methacrylic Acid SCHEMBL27385454 0.75 GLA (0.50) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL624043 0.75 GLA (0.41) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL7619289 0.74 TUBB4A (0.49) GLATDP1HDAC3HDAC4HDAC1
SCHEMBL221211 0.74 TDP1 (0.64) GLATDP1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107189395-B A kind of glass fibre reinforced poly carbonate composite and preparation method thereof 株洲时代新材料科技股份有限公司 2019-06-21 CN claimed
EP-2920236-B1 POLYMER COMPOSITION HAVING IMPROVED LONG-TERM STABILITY, MOULDED PARTS PRODUCED THEREFROM AND INTENDED USES THEREOF FRAUNHOFER GES FORSCHUNG (DE) 2019-06-05 EP claimed
CN-109825072-A A kind of fire-retardant nylon material of high tenacity and preparation method thereof 苏州斯英铂聚合材料有限公司 2019-05-31 CN claimed
CN-104704018-B The solid epoxy that core shell rubbers are modified 陶氏环球技术有限公司 2018-04-17 CN claimed
CN-105504738-B Halogen-free flame-retardant polycarbonate composite material and products thereof 苏州汉扬精密电子有限公司 2017-12-29 CN claimed
CN-104350155-B Method for producing methyl methacrylate 璐彩特国际英国有限公司 2017-10-31 CN claimed
CN-107189395-A A kind of glass fibre reinforced poly carbonate composite and preparation method thereof 株洲时代新材料科技股份有限公司 2017-09-22 CN claimed
CN-107177158-A It is a kind of to exempt from sprayed on material and preparation method thereof with metal-like 珠海市金塑塑料有限公司 2017-09-19 CN claimed
CN-106700473-A High-liquidity high-toughness reinforced PC composite material and preparing method thereof 合肥会通新材料有限公司 2017-05-24 CN claimed
US-20170044342-A1 FLAME-RETARDANT EXPANDABLE POLYMERS SUNPOR KUNSTSTOFF GESELLSCHAFT M.B.H. (AT) 2017-02-16 US claimed
CN-102702639-B Glass fiber reinforced styrene-acrylonitrile-N-phenylmaleimide-cyclic olefin copolymer compound NINGBO OCEANKING CHEMICAL DEV CO LTD 2014-04-23 CN claimed
CN-103131374-A Inorganic/organic nano particle compound modification epoxy resin adhesive and preparation method thereof INST PETROCHEMISTRY HEILONGJIANG ACADEMY OF SCIENCE 2013-06-05 CN claimed
US-20120264837-A1 Flameproof expandable polymerizates SUNPOR KUNSTSTOFF GES.m.b.H (AT) 2012-10-18 US claimed
US-20120184635-A1 Flameproof expandable polymerizates Sunpor Kunststoff Ges m.b.H. (AT) 2012-07-19 US claimed
EP-0858482-B1 MISCIBLE POLYMERS BAYER ANTWERPEN NV (BE) 2000-05-10 EP claimed
US-6060538-A IZOD IMPACT STRENGTH, BIAXIAL IMPACT ENERGY, DUCTILITY AND TENSILE ELONGATION WHILE MAINTAINING STIFFNESS AND FLEXURAL MODULUS; AS MOLDING MATERIALS; FOR INJECTION MOLDING, EXTRUSION MOLDING AND BLOW MOLDING GENERAL ELECTRIC COMPANY (US) 2000-05-09 US claimed
US-5905118-A ACRYLONITRILE-STYRENE COPOLYMERS WITH DIALKYLVINYL AROMATIC PHOSPHONATE BAYER ANTWERPEN S.A./N.V. (BE) 1999-05-18 US claimed
EP-0858482-A1 MISCIBLE POLYMERS BAYER ANTWERPEN N.V. (BE) 1998-08-19 EP claimed
WO-1997016487-A1 MISCIBLE POLYMERS BAYER ANTWERPEN S.A./N.V. (BE) 1997-05-09 WO claimed
US-4116908-A Process for the preparation of a master mixture for a powder composition with a polyvinyl chloride base EMERY GUY CHARLES 1978-09-26 US claimed