SCHEMBL3220470

SCHEMBL3220470

CC1(CC2CCC3CC2C3(C)C)CCC2C(C1)C2(C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.40
MAPK14 Q16539 1/20 0.40
CAMK1D Q8IU85 1/20 0.40
TBXA2R P21731 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
EPHX2 P34913 1/20 0.31
CXCR3 P49682 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2989495 0.76 ALDH1A1 (0.36)
SCHEMBL4411047 0.69 RET (0.46) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL2990859 0.69 RET (0.41) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL14393350 0.67 MAPK14 (0.49) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL14325015 0.67 MAPK14 (0.49) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL3702183 0.67 RET (0.45) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL8316378 0.67 RET (0.45) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL596246 0.67 RET (0.53) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL177080 0.67 MAPK14 (0.49) RETMAPK14CAMK1DTBXA2RHDAC6
SCHEMBL9426196 0.67 RET (0.49) RETMAPK14CAMK1DTBXA2RHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828283-B2 Traction fluids in toroidal continuously variable transmission (T-CVT) systems GENBERAL MOTORS CORPORATION 2004-12-07 US claimed
US-20040152931-A1 Traction fluid with alkane bridged dimer GM Global Technology Operations LLC 2004-08-05 US claimed
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
US-6828283-B2 Traction fluids in toroidal continuously variable transmission (T-CVT) systems GENBERAL MOTORS CORPORATION 2004-12-07 US disclosed
US-20040152931-A1 Traction fluid with alkane bridged dimer GM Global Technology Operations LLC 2004-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152931-A1 Traction fluid with alkane bridged dimer CCL11, CCL2, TLN1 RET 2395/4885MAPK14 1616/4885CAMK1D 1540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.