⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160974 | 0.81 | — | — | |
| SCHEMBL8198712 | 0.81 | — | — | |
| SCHEMBL10425 | 0.79 | — | — | |
| SCHEMBL2166098 | 0.78 | CES2 (0.71) | — | |
| SCHEMBL13237103 | 0.77 | — | — | |
| Iodide SCHEMBL28995246 | 0.77 | CES2 (0.62) | — | |
| SCHEMBL2815214 | 0.77 | — | — | |
| SCHEMBL845047 | 0.77 | — | — | |
| SCHEMBL3041357 | 0.75 | CES2 (0.54) | — | |
| SCHEMBL3036288 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579888-A2 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | Receptos, Inc. (US) | 2013-04-17 | — | — | EP | disclosed |
| US-8415272-B2 | Quinoline derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-09 | — | — | US | disclosed |
| WO-2011156655-A2 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | RECEPTOS, INC. (US) | 2011-12-15 | — | — | WO | disclosed |
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100056570-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-4569942-A | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents | PFIZER INC. (US) | 1986-02-11 | — | — | US | disclosed |