⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815214 | 1.00 | — | — | |
| SCHEMBL13237103 | 1.00 | — | — | |
| SCHEMBL9653531 | 0.82 | — | — | |
| SCHEMBL6815908 | 0.79 | CES2 (0.43) | — | |
| SCHEMBL13009934 | 0.79 | CES2 (0.43) | — | |
| SCHEMBL3220577 | 0.77 | — | — | |
| SCHEMBL8198712 | 0.75 | — | — | |
| SCHEMBL4160974 | 0.75 | — | — | |
| SCHEMBL9655883 | 0.74 | CES2 (0.39) | — | |
| SCHEMBL12360950 | 0.73 | CA9 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159417-B | Thienothiazole and derivative and synthetic method thereof | 湘潭大学 | 2023-06-13 | — | — | CN | claimed |
| CN-110669070-B | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2021-08-27 | — | — | CN | claimed |
| CN-110669070-A | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110294758-A | 2- replaces 5,6- dihydro-pyrazolo [5,1- α] isoquinolin, derivative and its synthetic method | 湘潭大学 | 2019-10-01 | — | — | CN | claimed |
| CN-112159417-B | Thienothiazole and derivative and synthetic method thereof | 湘潭大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-110606855-B | Polysubstituted benzothienoisoquinoline, derivative and synthesis method thereof | 湘潭大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-110669070-B | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2021-08-27 | — | — | CN | disclosed |
| EP-3652168-A1 | 5-MEMBERED AND BICYCLIC HETEROCYCLIC AMIDES AS INHIBITORS OF ROCK | Bristol-Myers Squibb Company (US) | 2020-05-20 | — | — | EP | disclosed |
| CN-110669070-A | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2020-01-10 | — | — | CN | disclosed |
| CN-110294758-A | 2- replaces 5,6- dihydro-pyrazolo [5,1- α] isoquinolin, derivative and its synthetic method | 湘潭大学 | 2019-10-01 | — | — | CN | disclosed |
| WO-2019014308-A1 | 5-MEMBERED AND BICYCLIC HETEROCYCLIC AMIDES AS INHIBITORS OF ROCK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-17 | — | — | WO | disclosed |
| US-9334274-B2 | N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2016-05-10 | — | — | US | disclosed |
| US-5530156-A | INTERMEDIATES FOR FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| US-5393920-A | Reacting oxime with lactone in presence of base | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-28 | — | — | US | disclosed |
| EP-0177924-B1 | (TETRAZOLYL)THIENOPYRIDINONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-02-21 | — | — | EP | disclosed |
| EP-0177065-B1 | THIENOTRIAZINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0177923-B1 | TETRAZOLOTHIENOPYRIDINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-03-01 | — | — | EP | disclosed |
| US-4593099-A | (Tetrazolyl) thienopyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-06-03 | — | — | US | disclosed |
| US-4581455-A | Tetrazolothienopyridines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-08 | — | — | US | disclosed |
| US-4581448-A | Thienotriazines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-08 | — | — | US | disclosed |