Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226151 | 0.83 | TDP1 (0.54) | TP53TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL3230298 | 0.75 | ALDH1A1 (0.52) | TSHRTDP1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL16957762 | 0.71 | TP53 (0.44) | TP53TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL16955144 | 0.71 | TP53 (0.44) | TP53TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL29556567 | 0.70 | ALDH1A1 (0.52) | TP53TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL1547285 | 0.70 | TP53 (0.48) | TP53TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL16961854 | 0.70 | TSHR (0.48) | TP53TSHRTDP1CYP3A4ALDH1A1 | |
| SCHEMBL820295 | 0.70 | ALDH1A1 (0.52) | TP53TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL42560 | 0.70 | TDP1 (0.67) | TP53TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL16955146 | 0.68 | TP53 (0.46) | TP53TSHRTDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | TP53 4316/4885TSHR 1014/4885TDP1 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.