Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825277 | 0.92 | GSK3A (0.61) | GSK3AGSK3BELANEPIN1PIN4 | |
| SCHEMBL668453 | 0.79 | TSHR (0.56) | GSK3AGSK3BELANEPIN1PIN4 | |
| SCHEMBL13143118 | 0.78 | GSK3A (0.58) | GSK3AGSK3BELANEPIN1PIN4 | |
| SCHEMBL6528311 | 0.77 | TSHR (0.50) | GSK3AGSK3BELANEPIN1PIN4 | |
| SCHEMBL5592121 | 0.76 | PLA2G10 (0.39) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL6495319 | 0.76 | TSHR (0.49) | GSK3AGSK3BELANEMEN1KMT2A | |
| SCHEMBL6818727 | 0.76 | GSK3A (0.47) | GSK3AGSK3BELANEPIN1PIN4 | |
| SCHEMBL15693392 | 0.75 | KMT2A (0.51) | GSK3AGSK3BELANEMEN1KMT2A | |
| SCHEMBL16223202 | 0.75 | TSHR (0.58) | GSK3AGSK3BELANEPIN1PIN4 | |
| SCHEMBL10139580 | 0.75 | CYP1A2 (0.43) | GSK3AGSK3BELANEPIN1PIN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003430-A1 | FORMULATIONS WITH POLYCARBOHYDRATESILOXANE COATINGS, THEIR PRODUCTION AND USE | PETHYLATION GMBH (DE) | 2010-01-14 | — | — | WO | disclosed |
| WO-2010003645-A1 | FORMULATIONS WITH POLYCARBOHYDRATESILOXANE COATINGS, THEIR PRODUCTION AND USE | PETHYLATION GMBH (DE) | 2010-01-14 | — | — | WO | disclosed |
| EP-1706420-A1 | SITE-SPECIFIC COUPLING OF POLYPEPTIDES | Pharmexa A/S (DK) | 2006-10-04 | — | — | EP | disclosed |
| EP-1689365-A1 | DRUG DELIVERY VEHICLES AND USES THEREOF | Pharmexa A/S (DK) | 2006-08-16 | — | — | EP | disclosed |
| EP-1689778-A1 | RGD TARGETING MOIETY ITS PORDUCTION AND USE | Pharmexa A/S (DK) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005070960-A1 | SITE-SPECIFIC COUPLING OF POLYPEPTIDES | PHARMEXA A/S (DK) | 2005-08-04 | — | — | WO | disclosed |
| EP-1557429-A1 | Site-directed coupling of proteins | Vectron Therapeutics AG (DE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2005053642-A1 | DRUG DELIVERY VEHICLES AND USES THEREOF | PHARMEXA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |
| WO-2005054293-A1 | RGD TARGETING MOIETY ITS PORDUCTION AND USE | PHARMEXA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |
| EP-1538164-A1 | RGD targeting moiety its production and use | Vectron Therapeutics AG (DE) | 2005-06-08 | — | — | EP | disclosed |
| EP-1537858-A1 | Drug delivery vehicles and uses thereof | Vectron Therapeutics AG (DE) | 2005-06-08 | — | — | EP | disclosed |
| US-20030064948-A1 | Invasomes for therapy of disorders, their preparation and use | VECTRON THERAPEUTICS AG (DE) | 2003-04-03 | — | — | US | disclosed |