Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532098 | 0.93 | PLA2G10 (0.40) | PLA2G10PLA2G5KDM4EALDH1A1POLB | |
| SCHEMBL29035758 | 0.82 | POLB (0.54) | POLBCCKBRMEN1KMT2A | |
| SCHEMBL1364804 | 0.79 | TSHR (0.54) | PLA2G10PLA2G5KDM4EALDH1A1POLB | |
| SCHEMBL22882469 | 0.79 | PLA2G10 (0.35) | PLA2G10PLA2G5KDM4EALDH1A1POLB | |
| SCHEMBL6334079 | 0.78 | TSHR (0.49) | PLA2G10PLA2G5KDM4EALDH1A1KMT2A | |
| SCHEMBL11042645 | 0.77 | TSHR (0.47) | PLA2G10PLA2G5KDM4EALDH1A1MEN1 | |
| SCHEMBL3221674 | 0.76 | GSK3A (0.58) | ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL4955615 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AHPGDTSHR | |
| SCHEMBL18969665 | 0.76 | PLA2G10 (0.36) | PLA2G10PLA2G5KDM4EALDH1A1POLB | |
| SCHEMBL10465762 | 0.75 | NPSR1 (0.49) | ALDH1A1POLBMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |