Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221983 | 1.00 | ALDH1A1 (0.55) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3217911 | 0.90 | EPHX2 (0.56) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3217921 | 0.90 | EPHX2 (0.56) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3224122 | 0.87 | MEN1 (0.52) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3224127 | 0.87 | MEN1 (0.52) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3213325 | 0.85 | MAPT (0.48) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3213333 | 0.85 | MAPT (0.48) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3208888 | 0.85 | MEN1 (0.53) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3212890 | 0.85 | MEN1 (0.44) | ALDH1A1EPHX2MEN1KMT2ARECQL | |
| SCHEMBL3212880 | 0.85 | MEN1 (0.44) | ALDH1A1EPHX2MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | claimed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | ALDH1A1 128/4885EPHX2 727/4885MEN1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.