SCHEMBL2448843

SCHEMBL2448843

[c]1ccccc1-c1ccccc1-c1ccccc1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
BCL2L1 Q07817 1/20 0.38
CYP2A6 P11509 1/20 0.38
MAPK1 P28482 1/20 0.38
PTGS2 P35354 1/20 0.35
BACE1 P56817 1/20 0.34
DPP4 P27487 1/20 0.34
MGLL Q99685 1/20 0.34
RAB9A P51151 1/20 0.34
RCE1 Q9Y256 1/20 0.34
GPR55 Q9Y2T6 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
NISCH Q9Y2I1 1/20 0.32
DCUN1D1 Q96GG9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769410 0.98 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL15863475 0.89 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL8855149 0.89 MEN1 (0.35) ALDH1A1HSD17B10MAPK1RAB9A
SCHEMBL322239 0.89 MEN1 (0.35) ALDH1A1HSD17B10MAPK1RAB9A
SCHEMBL2761711 0.86 MEN1 (0.32) ALDH1A1MAPK1RAB9A
SCHEMBL11721275 0.85
SCHEMBL9958209 0.82 NOTUM (0.41) ALDH1A1HSD17B10MAPK1RAB9A
SCHEMBL38202 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10BCL2L1CYP2A6MAPK1
SCHEMBL41140 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10BCL2L1CYP2A6MAPK1
SCHEMBL28586228 0.78 ESR1 (0.38) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US claimed
EP-1640430-B1 Luminescent material and organic electroluminescent device using the same JNC CORP (JP) 2011-09-21 EP disclosed
EP-2177586-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2010-04-21 EP disclosed
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP disclosed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same C1S, EPB41, EPB41L2 ALDH1A1 1227/4885HSD17B10 2775/4885HPGD 2934/4885
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 ALDH1A1 944/4885HSD17B10 1895/4885HPGD 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.