Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131766 | 1.00 | KCNH2 (0.32) | KCNH2ALDH1A1KDM4EMAPTCHRNA7 | |
| SCHEMBL3223010 | 1.00 | KCNH2 (0.32) | KCNH2ALDH1A1KDM4EMAPTCHRNA7 | |
| SCHEMBL3223462 | 0.86 | KCNH2 (0.32) | KCNH2SLC6A2SLC6A4 | |
| SCHEMBL10313858 | 0.86 | KCNH2 (0.32) | KCNH2SLC6A2SLC6A4 | |
| SCHEMBL2767755 | 0.84 | KDM4E (0.37) | KCNH2ALDH1A1KDM4EMAPTCHRNA7 | |
| Water SCHEMBL3517045 | 0.83 | KDM4E (0.37) | KCNH2ALDH1A1KDM4EMAPTSLC6A2 | |
| SCHEMBL4140059 | 0.80 | ALDH1A1 (0.36) | KCNH2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3223473 | 0.79 | KCNH2 (0.34) | KCNH2CHRNA7TSHR | |
| SCHEMBL4144883 | 0.76 | KCNH2 (0.33) | KCNH2ALDH1A1KDM4EMAPTCHRNA7 | |
| SCHEMBL3225911 | 0.74 | KDM4E (0.35) | KCNH2ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056502-A1 | COMPOUNDS | NRDC, NACA, NAA50 | KCNH2 3105/4885ALDH1A1 4233/4885KDM4E 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.