Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658777 | 0.80 | TRIM24 (0.34) | PLAUAXLSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7388303 | 0.78 | APLNR (0.58) | APLNRMIFPLAUNAAAALDH1A1 | |
| SCHEMBL13535994 | 0.77 | — | — | |
| SCHEMBL2931701 | 0.76 | APLNR (0.43) | APLNRMIFPLAUSMN1; SMN2MEN1 | |
| SCHEMBL29435535 | 0.76 | PLAU (0.52) | APLNRMIFPLAUMAPTKDM4E | |
| SCHEMBL2924950 | 0.76 | PLAU (0.52) | APLNRMIFPLAUMAPTKDM4E | |
| SCHEMBL384468 | 0.76 | APLNR (0.43) | APLNRMIFPLAUNAAASMN1; SMN2 | |
| SCHEMBL14037823 | 0.72 | — | — | |
| SCHEMBL22582894 | 0.72 | APLNR (0.40) | APLNRMIFMEN1KMT2AALDH1A1 | |
| SCHEMBL22583152 | 0.72 | PLAU (0.56) | APLNRMIFPLAUSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639337-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XWPharma Ltd. (KY) | 2023-05-02 | — | — | US | disclosed |
| WO-2010010184-A1 | [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010010184-A1 | [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639337-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | APLNR 2054/4885MIF 2266/4885PLAU 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.