Citric Acid

SCHEMBL322470

O=C([O-])CC(O)(CC(=O)OC(CC(=O)[O-])(CC(=O)[O-])C(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Ca+2].[Ca+2].[Ca+2].[Ca+2]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3A GSK3B HRH2 IMPA1

The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	CA4	P22748	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Potassium Ion SCHEMBL9243886	0.98	CA4 (0.55)	CA4
Citric Acid SCHEMBL24586	0.96	CA4 (0.57)	CA4
Potassium Ion SCHEMBL28994820	0.96	CA4 (0.57)	CA4
SCHEMBL2030766	0.96	CA4 (0.63)	CA4
SCHEMBL2150653	0.95	CA4 (0.61)	CA4
Potassium Ion SCHEMBL27876207	0.95	CA4 (0.55)	CA4
SCHEMBL29234711	0.90	CA4 (0.55)	CA4
Citric Acid SCHEMBL3633955	0.89	CA4 (0.46)	CA4
Citric Acid SCHEMBL19585410	0.86	CA4 (0.46)	CA4
SCHEMBL22227457	0.83	CA4 (0.50)	CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2310318-A2	POLYMERIC MATERIALS FOR ACTIVE FOOD PACKAGINGS	Universita' Degli Studi di Salerno (IT)	2011-04-20	—	—	EP	claimed