Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150653 | 0.98 | CA4 (0.61) | CA4 | |
| Citric Acid SCHEMBL24586 | 0.96 | CA4 (0.57) | CA4 | |
| Citric Acid SCHEMBL322470 | 0.96 | CA4 (0.57) | CA4 | |
| Potassium Ion SCHEMBL28994820 | 0.96 | CA4 (0.57) | CA4 | |
| Potassium Ion SCHEMBL27876207 | 0.95 | CA4 (0.55) | CA4 | |
| Potassium Ion SCHEMBL9243886 | 0.95 | CA4 (0.55) | CA4 | |
| SCHEMBL29234711 | 0.93 | CA4 (0.55) | CA4 | |
| Citric Acid SCHEMBL3633955 | 0.86 | CA4 (0.46) | CA4 | |
| Citric Acid SCHEMBL19585410 | 0.86 | CA4 (0.46) | CA4 | |
| SCHEMBL7121071 | 0.85 | CA4 (0.53) | CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172750-B | Immunosuppressive polypeptides and nucleic acids | ASTELLAS PHARMA INC | 2014-12-10 | — | — | CN | disclosed |
| CN-101998965-B | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC | 2014-03-12 | — | — | CN | disclosed |
| US-8496935-B2 | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC (US) | 2013-07-30 | — | — | US | disclosed |
| US-8491899-B2 | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC (US) | 2013-07-23 | — | — | US | disclosed |
| EP-2612868-A1 | Immunosuppressive polypeptides and nucleic acids | Perseid Therapeutics LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| EP-2612867-A1 | Immunosuppressive polypeptides and nucleic acids | Perseid Therapeutics LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| CN-103172750-A | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC | 2013-06-26 | — | — | CN | disclosed |
| US-8445230-B2 | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC (US) | 2013-05-21 | — | — | US | disclosed |
| EP-2222697-B1 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | PERSEID THERAPEUTICS LLC (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8318176-B2 | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-20110129875-A1 | IMMUNOSUPPRRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | PERSEID THERAPEUTICS LLC (US) | 2011-06-02 | — | — | US | disclosed |
| CN-101998965-A | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC | 2011-03-30 | — | — | CN | disclosed |
| US-20100260759-A1 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | PERSEID THERAPEUTICS LLC (US) | 2010-10-14 | — | — | US | disclosed |
| US-7794718-B2 | Immunosuppressive polypeptides and nucleic acids | Perseid Therapeutics, LLC (US) | 2010-09-14 | — | — | US | disclosed |
| EP-2222697-A2 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | Perseid Therapeutics LLC (US) | 2010-09-01 | — | — | EP | disclosed |
| US-20090258031-A1 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | MAXYGEN, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2009058564-A2 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | MAXYGEN, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| CN-1260357-C | Improved anti-IgE antibodies and method of improving polypeptides | GENENTECH INC (US) | 2006-06-21 | — | — | CN | disclosed |
| JP-2004315439-A | LIQUID COMPOSITION FOR INTERNAL USE CONTAINING IRON COMPOUND | TAISHO PHARMACEUT CO LTD | 2004-11-11 | — | — | JP | disclosed |
| CN-1268176-A | Improved anti-IgE antibodies and method of improving polypeptides | GENENTECH INC (US) | 2000-09-27 | — | — | CN | disclosed |