Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212875 | 1.00 | CYP2A6 (0.32) | CYP2A6KDM4EALDH1A1 | |
| SCHEMBL8632759 | 0.92 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL4622730 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL55697 | 0.84 | KDM4E (0.34) | CYP2A6KDM4E | |
| SCHEMBL4608629 | 0.83 | KDM4E (0.33) | CYP2A6KDM4E | |
| Cyclohexane SCHEMBL8638010 | 0.82 | KDM4E (0.32) | CYP2A6KDM4EALDH1A1 | |
| SCHEMBL4925150 | 0.77 | PDGFRB (0.34) | CYP2A6KDM4E | |
| SCHEMBL1246522 | 0.76 | KDM4E (0.36) | CYP2A6KDM4E | |
| Cyclohexylamine SCHEMBL1254606 | 0.76 | SMYD3 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL4926350 | 0.74 | FLT3 (0.34) | CYP2A6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227584-B2 | Ostertagia vaccine | UNIVERSITEIT GENT (NL) | 2012-07-24 | — | — | US | disclosed |
| US-20100209446-A1 | Ostertagia Vaccine | UNIVERSITEIT GENT | 2010-08-19 | — | — | US | disclosed |
| US-7718179-B2 | Ostertagia ostertagi proteins; immunogenic composition | UNIVERSITEIT GENT (BE) | 2010-05-18 | — | — | US | disclosed |
| WO-2010018592-A2 | LETHAL GENE AS A TOOL FOR ZERO BACKGROUND CLONING | LUPIN LIMITED (IN) | 2010-02-18 | — | — | WO | disclosed |
| US-20090028892-A1 | Ostertagia Vaccine | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
| EP-1539820-B1 | OSTERTAGIA VACCINE | UNIV GENT (BE) | 2008-04-16 | — | — | EP | disclosed |
| US-7264812-B2 | Ostertagia vaccine | UNIVERSITEIT GENT (BE) | 2007-09-04 | — | — | US | disclosed |
| US-20050271683-A1 | Ostertagia vaccine | UNIVERSITEIT GENT (BE) | 2005-12-08 | — | — | US | disclosed |
| US-20050227345-A1 | Quorum sensing signaling in bacteria | AURORA BIOSCIENCES CORPORATION (US) | 2005-10-13 | — | — | US | disclosed |
| EP-1539820-A2 | OSTERTAGIA VACCINE | UNIVERSITEIT GENT (BE) | 2005-06-15 | — | — | EP | disclosed |
| US-6855513-B1 | Quorum sensing signaling in bacteria | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2004083385-A2 | QUORUM SENSING SIGNALING IN BACTERIA | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2004-09-30 | — | — | WO | disclosed |
| WO-2004024769-A2 | OSTERTAGIA VACCINE | UNIVERSITEIT GENT (BE) | 2004-03-25 | — | — | WO | disclosed |
| US-20040052817-A1 | Ostertagia vaccine | GELDHOF PETER (BE) | 2004-03-18 | — | — | US | disclosed |
| US-20040033549-A1 | Identifying modulator of biofilm formation and/or infection for treatment and prevention of infections, skin, periodontal and respiratory system disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-19 | — | — | US | disclosed |
| EP-1250450-A2 | QUORUM SENSING SIGNALING IN BACTERIA | University of Iowa Research Foundation Inc. (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001018248-A2 | QUORUM SENSING SIGNALING IN BACTERIA | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2001-03-15 | — | — | WO | disclosed |
| WO-2000015846-A1 | ZERO BACKGROUND UNIVERSAL CLONING METHOD | HYMAN EDWARD DAVID (US) | 2000-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227345-A1 | Quorum sensing signaling in bacteria | PGLS, Q6ZSR9, FDPS | CYP2A6 3681/4885KDM4E 1625/4885ALDH1A1 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.