Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 8/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227460 | 0.87 | PTGDR (0.46) | HRH1HRH4VCPSYKBRAF | |
| SCHEMBL3232266 | 0.84 | HRH1 (0.45) | HRH1HRH4VCPBRAFPTGDR | |
| SCHEMBL3234459 | 0.81 | CAMK2D (0.45) | VCPSYKMEN1KMT2A | |
| SCHEMBL3420476 | 0.81 | CAMK2D (0.45) | VCPSYKMEN1KMT2A | |
| SCHEMBL3221036 | 0.77 | PTGDR (0.47) | HRH4VCPSYKPTGDR | |
| SCHEMBL3225921 | 0.76 | ADORA1 (0.36) | VCPSLC2A1MEN1KMT2A | |
| SCHEMBL13456904 | 0.74 | VCP (0.48) | HRH1HRH4VCP | |
| SCHEMBL3236008 | 0.74 | PTGDR (0.45) | HRH1HRH4VCPSYKPTGDR | |
| SCHEMBL3261619 | 0.73 | VCP (0.42) | VCPSYKPTGDR | |
| SCHEMBL3235448 | 0.72 | SYK (0.42) | VCPSYKNPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | claimed |
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |