Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 18/20 | 0.47 |
| ▸ | GALR1 | P47211 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230131 | 0.98 | VCP (0.47) | VCPGALR1 | |
| SCHEMBL13456811 | 0.92 | VCP (0.44) | VCPGALR1 | |
| SCHEMBL3227529 | 0.91 | VCP (0.51) | VCPGALR1 | |
| SCHEMBL3228932 | 0.89 | VCP (0.51) | VCPGALR1 | |
| SCHEMBL3223357 | 0.84 | SMN1; SMN2 (0.38) | VCPALDH1A1 | |
| SCHEMBL3237759 | 0.82 | VCP (0.38) | VCPALDH1A1 | |
| SCHEMBL3228961 | 0.82 | MAPT (0.47) | VCP | |
| SCHEMBL3423997 | 0.80 | PTGS2 (0.39) | VCPALDH1A1 | |
| SCHEMBL3420464 | 0.79 | PTGS2 (0.39) | VCPALDH1A1 | |
| SCHEMBL13456904 | 0.77 | VCP (0.48) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144722-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-06-10 | — | — | US | disclosed |
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144722-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | GATAD2B, GATAD2A, RUNX1 | VCP 4664/4885GALR1 725/4885ALDH1A1 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.