Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FHIT | P49789 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219368 | 0.80 | ALDH1A1 (0.58) | HTTKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL15678751 | 0.80 | ALDH1A1 (0.48) | HTTKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4687946 | 0.80 | RCE1 (0.43) | HTTKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL924712 | 0.77 | RPA1 (0.56) | HTTKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL11643715 | 0.76 | MAPK1 (0.41) | HTTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10642406 | 0.76 | HTT (0.58) | HTTKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL16474745 | 0.76 | MAPK1 (0.52) | HTTKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL11519772 | 0.76 | KMT2A (0.55) | HTTKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL11150434 | 0.74 | CA1 (0.55) | HTTKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11589591 | 0.74 | ABHD16A (0.51) | HTTKMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107446840-A | One plant of 2 pyridazinone degradation bacteria of 6 hydroxyl of phenyl 3 and its application | 江苏南资环保股份有限公司 | 2017-12-08 | — | — | CN | claimed |
| US-20070191368-A1 | Inhibition of tissue damage to skin from radiation treatment therapy | BISSETT DONALD L | 2007-08-16 | — | — | US | claimed |
| WO-2003002119-A1 | TREATMENT AND PREVENTION OF LIPODERMATOSCLEROSIS | JOHNSON & JOHNSON MEDICAL LIMITED (GB) | 2003-01-09 | — | — | WO | claimed |
| US-5780459-A | SALICYLIC ACID WITH ADDITIONAL ACTIVE MATERIALS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-14 | — | — | US | claimed |
| US-5487884-A | CYTOPROTECTIVE AGENTS BY RADIATION RESISTANCE TO PREVENT SKIN CANCER AND PREMATURE AGING | THE PROCTER & GAMBLE COMPANY (US) | 1996-01-30 | — | — | US | claimed |
| EP-0313305-A2 | Photoprotection compositions comprising chelating agents | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| JP-2306984-A | — | — | None | — | — | JP | disclosed |
| CN-107446840-A | One plant of 2 pyridazinone degradation bacteria of 6 hydroxyl of phenyl 3 and its application | 江苏南资环保股份有限公司 | 2017-12-08 | — | — | CN | disclosed |
| US-9562019-B2 | Substituted pyridazines as EGFR and/or KRAS inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-02-07 | — | — | US | disclosed |
| US-9562019-B2 | Substituted pyridazines as EGFR and/or KRAS inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-02-07 | — | — | US | disclosed |
| US-20130131062-A1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | DJABALLAH HAKIM (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131062-A1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | DJABALLAH HAKIM (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012006107-A2 | SKIN CARE COMPOSITIONS | STEMTIDE, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| JP-H02306984-A | INDUSTRIAL PRODUCTION OF ORGANIC PHOSPHORIC ESTER DERIVATIVE | NIPPON KAYAKU CO LTD | 1990-12-20 | — | — | JP | disclosed |
| EP-0400430-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0313305-A2 | Photoprotection compositions comprising chelating agents | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0258391-A1 | USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD | RHONE POULENC NEDERLAND B.V. (NL) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004321-A2 | USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD | RHONE-POULENC NEDERLANDS B.V. (NL) | 1987-07-30 | — | — | WO | disclosed |
| US-4155997-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |
| US-4112081-A | INSECTICIDE, MITICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131062-A1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | DPYD, PDXK, TYMP | HTT 3777/4885KMT2A 3872/4885MAPT 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.