Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.57 |
| ▸ | PRKACA | P17612 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.55 |
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.55 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.55 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | FLT4 | P35916 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235893 | 0.90 | CSNK1D (0.56) | MAPTCSNK1DROCK1PRKACARAB9A | |
| SCHEMBL3232502 | 0.90 | ROCK1 (0.49) | MAPTCSNK1DROCK1PRKACAUSP2 | |
| SCHEMBL3237711 | 0.89 | ROCK1 (0.49) | MAPTCSNK1DROCK1PRKACAUSP2 | |
| SCHEMBL3233424 | 0.89 | ROCK1 (0.49) | MAPTCSNK1DROCK1PRKACAUSP2 | |
| SCHEMBL3226719 | 0.89 | ROCK1 (0.50) | MAPTCSNK1DROCK1PRKACARAB9A | |
| SCHEMBL1681023 | 0.88 | ROCK1 (0.54) | MAPTROCK1USP2KDM6BKDM5A | |
| SCHEMBL3232672 | 0.88 | ROCK1 (0.48) | MAPTCSNK1DROCK1PRKACAUSP2 | |
| SCHEMBL13491695 | 0.88 | RAB9A (0.63) | MAPTCSNK1DROCK1KDM4CRAB9A | |
| SCHEMBL3233383 | 0.88 | CSNK1D (0.49) | MAPTCSNK1DROCK1RAB9AMEN1 | |
| SCHEMBL13491574 | 0.87 | ROCK1 (0.53) | MAPTROCK1USP2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024365-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | claimed |
| WO-2010024365-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |