Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.49 |
| ▸ | DRD1 | P21728 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812726 | 0.98 | KCNH2 (0.47) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL4806424 | 0.94 | CYP2D6 (0.50) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL16491446 | 0.91 | CHRM2 (0.60) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL16491448 | 0.91 | CHRM2 (0.60) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL16491466 | 0.91 | CHRM2 (0.60) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL16491456 | 0.91 | CHRM2 (0.60) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL16491470 | 0.91 | CHRM2 (0.60) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL38656961 | 0.91 | CYP2D6 (0.53) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL10654586 | 0.89 | HRH1 (0.43) | KCNH2CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL16491465 | 0.88 | KCNH2 (0.47) | KCNH2CHRM2ADRA2ADRD1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-07-15 | — | — | US | claimed |
| WO-2008121074-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-10-09 | — | — | WO | claimed |
| US-6692905-B2 | COLOR PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-17 | — | — | US | claimed |
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-07-15 | — | — | US | disclosed |
| US-7622486-B2 | Pyridine compounds, process for their preparation and compositions containing them | REDDY US THERAPEUTICS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| EP-1805142-A4 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS INC (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008121074-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-10-09 | — | — | WO | disclosed |
| EP-1805142-A2 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1759713-A2 | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1749516-A2 | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-02-07 | — | — | EP | disclosed |
| EP-1007011-B1 | LOCK AND KEY MICELLES | UNIV SOUTH FLORIDA (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20020012892-A1 | Methine compound-containing silver halide photographic emulsion and photographic material using the same | FUJIFILM CORPORATION (JP) | 2002-01-31 | — | — | US | disclosed |
| EP-0771190-A4 | LOCK AND KEY MICELLES | UNIV SOUTH FLORIDA (US) | 2000-12-20 | — | — | EP | disclosed |
| US-6130209-A | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-10-10 | — | — | US | disclosed |
| EP-1007011-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5863919-A | Lock and key micelles and monomer building blocks therefor | UNIVERSITY OF SOUTH FLORIDA (US) | 1999-01-26 | — | — | US | disclosed |
| WO-1998008491-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 1998-03-05 | — | — | WO | disclosed |
| US-5650101-A | Lock and key micelles | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0771190-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996003114-A1 | LOCK AND KEY MICELLES | UNIVERSITY OF SOUTH FLORIDA (US) | 1996-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | TDO2, AOX1, DAO | KCNH2 920/4885CHRM2 432/4885ADRA2A 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.