Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498714 | 0.79 | CYP3A4 (0.39) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL3218445 | 0.74 | CYP3A4 (0.36) | TSHRHSD17B10CYP3A4GRIN2DGRIN3B | |
| SCHEMBL3539564 | 0.71 | KDM4E (0.36) | ALDH1A1TSHRCES1HSD17B10KDM4E | |
| SCHEMBL11218287 | 0.70 | TSHR (0.38) | ALDH1A1TSHRCES1CYP3A4 | |
| SCHEMBL3226561 | 0.68 | S100A4 (0.39) | ALDH1A1TSHRCES1GRIN2DGRIN3B | |
| SCHEMBL11283900 | 0.68 | — | — | |
| SCHEMBL3223624 | 0.66 | — | — | |
| SCHEMBL6839545 | 0.65 | AHR (0.33) | CES1CYP3A4 | |
| SCHEMBL6908764 | 0.64 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11657600 | 0.63 | KDM4E (0.31) | ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015037-A1 | THERAPEUTIC METHODS AND COMPOSITIONS | HOWARD FLOREY INSTITUTE (AU) | 2010-02-11 | — | — | WO | disclosed |