SCHEMBL3226848

SCHEMBL3226848

O=c1[nH]c2cc(Cl)cc(Cl)c2[nH]1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 8/20 0.70
GRIN2D O15399 7/20 0.70
GRIN3B O60391 7/20 0.70
GRIN2A Q12879 7/20 0.70
GRIN2B Q13224 7/20 0.70
GRIN2C Q14957 7/20 0.70
GRIN3A Q8TCU5 7/20 0.70
ALDH1A1 P00352 3/20 0.70
KDM4E B2RXH2 2/20 0.70
HSD17B10 Q99714 2/20 0.70
GAA P10253 1/20 0.70
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
HPGD P15428 2/20 0.43
TSHR P16473 2/20 0.43
BLM P54132 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2639494 0.83 GRIN2D (1.00) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL3489785 0.79 GRIN2D (0.46) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL8872169 0.79 GRIN2D (0.85) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL19781547 0.79 GRIN2D (0.47) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL17488223 0.79 GRIN2D (0.46) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL16599563 0.79 ALDH1A1 (0.46) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL3669227 0.75 GRIN2D (0.51) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL3423565 0.75 KDM4E (0.50) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL24549462 0.75 DRD2 (0.48) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
SCHEMBL21982937 0.75 GRIN2D (0.42) GRIN1GRIN2DGRIN3BGRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed
WO-2010015037-A1 THERAPEUTIC METHODS AND COMPOSITIONS HOWARD FLOREY INSTITUTE (AU) 2010-02-11 WO disclosed